CASP3 Target T0051

1. Protein Name

Glutamate mutase, component E

2. Organism Name

Clostridium cohlearium

3. Number of amino acids (approx)

1240 (compE 483, compS 137)

4. Accession number

X80997

5. Sequence Database

EMBL

6. Amino acid sequence

>gi|2127335|pir||I40658 methylaspartate mutase (EC 5.4.99.1) component S - Clostridium cochlearium
MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQEVFIKAAIETKADAILLSSLYGQGEID
CKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE
>gi|2127336|pir||I40662 methylaspartate mutase (EC 5.4.99.1) conponent E - Clostridium cochlearium
MELKNKKWTDEEFHKQREEVLQQWPTGKEVDLQEAVDYLKKIPAEKNFAEKLVLAKKKGITMAQPRAGVA
LLDEHIELLRYLQDEGGADFLPSTIDAYTRQNRYDECENGIKESEKAGRSLLNGFPGVNYGVKGCRKVLE
AVNLPLQARHGTPDSRLLAEIIHAGGWTSNEGGGISYNVPYAKNVTIEKSLLDWQYCDRLVGFYEEQGVH
INREPFGPLTGTLVPPSMSNAVGITEALLAAEQGVKNITVGYGECGNMIQDIAALRCLEEQTNEYLKAYG
YNDVFVTTVFHQWMGGFPQDESKAFGVIVTATTIAALAGATKVIVKTPHEAIGIPTKEANAAGIKATKMA
LNMLEGQRMPMSKELETEMAVIKAETKCILDKMFELGKGDLAIGTVKAFETGVMDIPFGPSKYNAGKMMP
VRDNLGCVRYLEFGNVPFTEEIKNYNRERLQERAKFEGRDVSFQMVIDDIFAVGKGRLIGRPE

7. Homologous Sequence of known structure

yes

8. Current state of the experimental work

We have two heavyatom derivatives and native dataset.
Crystals diffract to 1.7 Angstrom.
Even though at the moment structure determination is running
very positively, we can not incure that the structure is
ready 1. September 1998.

9. Interpretable map?

no

10. Estimated date of chain tracing completion

Summer 1998

11. Estimated date of public release of structure

End of 1998

12. Additional Information

Glutamate mutase is a HETEROTETRAMER, composed of two components S and E.
The component S shows high sequence similarity with the B12-binding domains
of methylmalonyl CoA mutase (P. shermanii) and methionine synthase (E. coli).

13. Name

unavailable until after public release of structure

Related Files

Template PDB file