Abstract: We determined and annotated the complete 2.2-megabase genome sequence of Pyrobaculum aerophilum, a facultatively aerobic nitrate-reducing hyperthermophilic (T(opt) = 100 degrees C) crenarchaeon. Clues were found suggesting explanations of the organism's surprising intolerance to sulfur, which may aid in the development of methods for genetic studies of the organism. Many interesting features worthy of further genetic studies were revealed. Whole genome computational analysis confirmed experiments showing that P. aerophilum (and perhaps all crenarchaea) lack 5' untranslated regions in their mRNAs and thus appear not to use a ribosome-binding site (Shine-Dalgarno)-based mechanism for translation initiation at the 5' end of transcripts. Inspection of the lengths and distribution of mononucleo... [Click above reference link for full abstract]
A genome position can be specified by chromosomal coordinate range, COG
ID, or keywords from the GenBank or TIGR description of a gene.
The available chromosome/plasmid names are:
Browser Chrom/Plasmid Name | Length (bp) | GC Content (%) | Gene Count | NCBI RefSeq Accession |
---|---|---|---|---|
chr | 2222430 | 51.36 | 2706 | NC_003364 |
The following list shows examples of valid position queries for this genome:
Request: | Genome Browser Response: |
---|---|
chr | Displays the entire sequence "chr" in the browser window |
chr:1-10000 | Displays first ten thousand bases of the sequence "chr" |
transporter | Lists all genes with "transporter" in the name or description |
PAE0014 | Display genome at position of gene PAE0014 |
If you use the browser in your published research, please cite our publication in the Nucleic Acids Research Database Issue. Citations and positive feedback will help us obtain funding to continue development of this community resource.