The Halobacterium sp. NRC-1 genome is 2.57 Million bp long and contains approximately 2674 predicted genes. Halobacterium is a halophilic aerobic euryarchaeon found under conditions of extremely high salinity, at an optimum of 4.3M salt. It is a mesophile which grows optimally at 42C. A well-developed genetic system is available for this species.

The sequence was released Oct 2000 by the University of Massachusetts-Amherst, University of Washington, and was described in Proc Natl Acad Sci U S A 97:12176-81 (2000) Ng WV, Kennedy SP, Mahairas GG, Berquist B, Pan M, et al.  "Genome sequence of Halobacterium species NRC-1. "
Abstract: We report the complete sequence of an extreme halophile, Halobacterium sp. NRC-1, harboring a dynamic 2,571,010-bp genome containing 91 insertion sequences representing 12 families and organized into a large chromosome and 2 related minichromosomes. The Halobacterium NRC-1 genome codes for 2,630 predicted proteins, 36% of which are unrelated to any previously reported. Analysis of the genome sequence shows the presence of pathways for uptake and utilization of amino acids, active sodium-proton antiporter and potassium uptake systems, sophisticated photosensory and signal transduction pathways, and DNA replication, transcription, and translation systems resembling more complex eukaryotic organisms. Whole proteome comparisons show the definite archaeal nature of this halophile with additiona... [Click above reference link for full abstract]

Sample position queries

A genome position can be specified by chromosomal coordinate range, COG ID, or keywords from the GenBank or TIGR description of a gene. The available chromosome/plasmid names are:

Browser Chrom/Plasmid NameLength (bp)GC Content (%)Gene CountNCBI RefSeq Accession
plasmid_pNRC10019134657.91176NC_001869
chr201423967.912127NC_002607
plasmid_pNRC20036542559.22371NC_002608

The following list shows examples of valid position queries for this genome: 

Request:Genome Browser Response:
chrDisplays the entire sequence "chr" in the browser window
chr:1-10000    Displays first ten thousand bases of the sequence "chr"
transporter    Lists all genes with "transporter" in the name or description
VNG7010Display genome at position of gene VNG7010


Credits

The Archaeal Genome Browsers at UCSC were developed by members of the Lowe Lab (Kevin Schneider, Katherine Pollard, Andy Pohl, Todd Lowe) and Robert Baertsch, with significant support from the UCSC Human Genome Browser group. The Archaeal Browsers are run by a slightly modified version of the UCSC Human Genome Browser system. All queries, bug reports, content corrections, suggested improvements, and new track data submissions should be sent to Todd Lowe (lowe @soe.ucsc.edu).

If you use the browser in your published research, please cite our publication in the Nucleic Acids Research Database Issue. Citations and positive feedback will help us obtain funding to continue development of this community resource.