Abstract: Methanosphaera stadtmanae has the most restricted energy metabolism of all methanogenic archaea. This human intestinal inhabitant can generate methane only by reduction of methanol with H2 and is dependent on acetate as a carbon source. We report here the genome sequence of M. stadtmanae, which was found to be composed of 1,767,403 bp with an average G+C content of 28% and to harbor only 1,534 protein-encoding sequences (CDS). The genome lacks 37 CDS present in the genomes of all other methanogens. Among these are the CDS for synthesis of molybdopterin and for synthesis of the carbon monoxide dehydrogenase/acetyl-coenzyme A synthase complex, which explains why M. stadtmanae cannot reduce CO2 to methane or oxidize methanol to CO2 and why this archaeon is dependent on acetate for biosynthesi... [Click above reference link for full abstract]
A genome position can be specified by chromosomal coordinate range, COG
ID, or keywords from the GenBank or TIGR description of a gene.
The available chromosome/plasmid names are:
Browser Chrom/Plasmid Name | Length (bp) | GC Content (%) | Gene Count | NCBI RefSeq Accession |
---|---|---|---|---|
chr | 1767403 | 27.63 | 1588 | NC_007681 |
The following list shows examples of valid position queries for this genome:
Request: | Genome Browser Response: |
---|---|
chr | Displays the entire sequence "chr" in the browser window |
chr:1-10000 | Displays first ten thousand bases of the sequence "chr" |
transporter | Lists all genes with "transporter" in the name or description |
Msp_0010 | Display genome at position of gene Msp_0010 |
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