The Escherichia coli O157:H7 genome is 5.59 Million bp long and contains approximately 5483 predicted genes.

The sequence was released 03/29/2000 by the Osaka Univ., and was described in DNA Res 8:11-22 (2001) Hayashi T, Makino K, Ohnishi M, Kurokawa K, Ishii K, et al.  "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12. "
Abstract: Escherichia coli O157:H7 is a major food-borne infectious pathogen that causes diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome. Here we report the complete chromosome sequence of an O157:H7 strain isolated from the Sakai outbreak, and the results of genomic comparison with a benign laboratory strain, K-12 MG1655. The chromosome is 5.5 Mb in size, 859 Kb larger than that of K-12. We identified a 4.1-Mb sequence highly conserved between the two strains, which may represent the fundamental backbone of the E. coli chromosome. The remaining 1.4-Mb sequence comprises of O157:H7-specific sequences, most of which are horizontally transferred foreign DNAs. The predominant roles of bacteriophages in the emergence of O157:H7 is evident by the presence of 24 prophages and prophage-like el... [Click above reference link for full abstract]

Sample position queries

A genome position can be specified by chromosomal coordinate range, COG ID, or keywords from the GenBank or TIGR description of a gene. The available chromosome/plasmid names are:

Browser Chrom/Plasmid NameLength (bp)GC Content (%)Gene CountNCBI RefSeq Accession
plasmid_pOSAK1330643.413NC_002127
plasmid_pO1579272147.6085NC_002128
chr549845050.545395NC_002695

The following list shows examples of valid position queries for this genome: 

Request:Genome Browser Response:
chrDisplays the entire sequence "chr" in the browser window
chr:1-10000    Displays first ten thousand bases of the sequence "chr"
transporter    Lists all genes with "transporter" in the name or description
pO157p06Display genome at position of gene pO157p06


Credits

The Archaeal Genome Browsers at UCSC were developed by members of the Lowe Lab (Kevin Schneider, Katherine Pollard, Andy Pohl, Todd Lowe) and Robert Baertsch, with significant support from the UCSC Human Genome Browser group. The Archaeal Browsers are run by a slightly modified version of the UCSC Human Genome Browser system. All queries, bug reports, content corrections, suggested improvements, and new track data submissions should be sent to Todd Lowe (lowe @soe.ucsc.edu).

If you use the browser in your published research, please cite our publication in the Nucleic Acids Research Database Issue. Citations and positive feedback will help us obtain funding to continue development of this community resource.