Alison Tang

Graduate Student at UC Santa Cruz



Me

I am a scientist in training. UC Berkeley is my alma mater, where I studied genetics in the molecular and cell biology department as well as some computer science. I hope to continue to learn and apply and develop computational approaches for solving biological problems. My interests include precision genomics, mRNA splicing, complex inheritance and the missing heritability problem, and gene regulation.


The Present

I'm a second year graduate student at UC Santa Cruz studying bioinformatics. I am a student in Angela Brooks' lab working on a project using nanopore sequencing to investigate the transcriptome and SF3B1, which is associated with 3' splicing of pre-mRNA.





The Past

Research projects I participated in


Epigenetic inheritance

With Dr. Dario Boffelli, I worked on investigating patterns of epigenetic inheritance by comparing transcriptome data between isogenic mice with and without their genomes repatterned with ethanol.

Fly Evolution

With Dr. Russell Corbett-Detig in Rasmus Nielsen's research group, I worked on identifying chromosomal inversions in D. melanogaster genomes by clustering them based on similarity measures near inversion breakpoints. I also worked on developing statistical methods for identifying loci experiencing selection between chromosomal inversions in populations.

LncRNAs and Reprogramming

In my previous rotation with Dr. Daniel Kim, I investigated the relationship between transposable element content (location in transcript, transposon type, associated clade) and lncRNAs activated during reprogramming in mouse and human cell lines.