Citations (SAM, SAM-T99, HMMs)
10 20 30 40 50
| | | | |
1 MSAVTESVLESIISP.VTMSEFLEEYW.PVKPLVARGEVE.....RF.....TS..IPGFEKVRT
2 ---------------.LNWPDFLERHW.QKRPVVLKRGFN.....NF.....ID..PISPDELAG
3 ---------------.LNWPDFLERHW.QKRPVVLKRGFN.....NF.....ID..PISPDELAG
4 ---------------.LNWPDFLERHW.QKRPVVLKRGFN.....NF.....ID..PISPDELAG
5 ---------------.LNWPDFLERHW.QKRPVVLKRGFN.....NF.....ID..PISPDELAG
6 ---------------.LNWPDFLERHW.QKRPVVLKRGFN.....NF.....ID..PISPDELAG
7 ---------------.LNWPDFLERHW.QKRPVVLKRGFS.....NF.....ID..PLSPDELAG
8 ---------------.LNWPDFLERHW.QKRPVVLKRGFT.....NF.....ID..PLSPDELAG
9 --------------D.LDWPDFLQRYW.QKRPVILKRGFK.....NF.....ID..PLSPDELAG
10 ---------------.LDWPDFLQRYW.QKRPVILKRGFK.....NF.....ID..PLSPDELAG
11 ---------------.LDWQAFLHNHW.QKRPLLIKQGFR.....QF.....ID..PLTPDELAG
12 NFDSPSSFFESLISP.IKVETFFKEFW.EQKPLLIQRDDPslaa.YY.....QS..LFSLSDLRS
13 ------DIPLQFLGG.ISAREFLRDYW.QKRPLLIRQAVP.....GF.....ES..PISPDELAG
14 --AVTESVLESIISP.VTMSEFLEEYW.PVKPLVARGEVE.....RF.....TS..IPGFEKVRT
15 --------------G.MPEEYFLHRYW.QKRPLLIRNAFP.....DF.....HS..PVTPEDLAG
16 --------------G.MPEEYFLHHYW.QKRPLLIRNAFP.....DF.....HS..PVTPEDLAG
17 --------------G.MPEEYFLHHYW.QKRPLLIRNAFP.....DF.....HS..PVTPEDLAG
18 -------TPLQLLGG.LTAAEFLRDYW.QRKPLLVRQAIP.....DF.....ES..PLSADELAG
19 ------DIPLQLLGG.ISARVFLRDYW.QKKPLLIRQALP.....DF.....QS..PIDADELAG
20 -------TPLQLLGG.LTAAEFLRDYW.QRKPLLVRQAIP.....DF.....ES..PLSADELAG
21 ------DIPLQFLGG.ISARVFLRDYW.QKKPLLIRQALP.....DF.....QS..PIDADELAG
22 --------------G.MPEEYFLHHYW.QKRSLLIRNAFP.....DF.....HS..PVTPEDLAG
23 NFDSPSSLFESLISP.IKTETFFKEFW.EQKPLLIQRDDPalat.YY.....GS..LFKLTDLKS
24 NFDSPSSLFESLISP.IKTETFFKEFW.EQKPLLIQRDDPalat.YY.....GS..LFKLTDLKS
25 NFDSPSSLFESLISP.IKTETFFKEFW.EQKPLLIQRDDPalat.YY.....GS..LFKLTDLKS
26 NFDSPSSFFESLISP.IKVETFFKEFW.EQKPLLIQRDDPvlak.YY.....QS..LFSLSDLKR
27 NFDSPSSLFESLISP.IKTETFFKEFW.EQKPLLIQRDDPalat.YY.....GS..LFKLTDLKS
28 NFDSPSSFFESLISP.IKVETFFKEFW.EQKPLLIQRDDPvlak.YY.....QS..LFSLSDLKR
29 NFDSPSSFFESLISP.IKVETFFKEFW.EQKPLLIQRDDPvlak.YY.....QS..LFSLSDLKR
30 NFDSPSSFFESLISP.IKVETFFKEFW.EQKPLLIQRDDPslaa.YY.....QS..LFSLSDLKS
31 ------DTPLQLLGG.ISAREFMRDYW.QKKPLLVRQAFP.....DF.....IS..PIDPDELAG
32 --------------G.MPVERFLRNYW.HKHPLLIRNAFA.....DF.....AS..PLQPEDLAG
33 ---------------.-------RDYW.QKKPLLIRQAIP.....DF.....ES..PIDADELAG
34 ------------LGD.MPIETFLRDYW.QKKPLLIRQALP.....NF.....ES..PLSADELAG
35 ---------------.--FEEFLAEFW.QKKPVVIKGGFK.....DF.....VD..PISPDELAG
36 --------------G.MPVERFLRTYW.HKHPLLIRNAFP.....DF.....QS..PLQPEDLAG
37 ---------------.-------RRYW.QKKPLLIRQAIP.....GV.....KP..PLTRDALFD
38 ---------------.-------RGYW.QKKPLLIRQAIP.....GV.....AS..PVTRDALFE
39 ------SVDFCLPEH.ITPEIFLRDYW.QKKPLVIRNGLP.....EI.....VG..QFEPQDIIE
40 ------SVDFCLPEH.ITPEIFLRDYW.QKKPLVIRNGLP.....EI.....VG..QFEPQDIIE
41 -----------LLGG.MPPEQFLAEYW.HKKPLLIRGALT.....DV.....GP..HVDFSVLSE
42 -VVTSSRAFGFMISP.CDVQTFFDKFY.QSNVLVVRRKQPtyfg.NL.....FS..TARLGELLE
43 -----------LLGN.LTPSQFMRRYW.QKKPLLIRQAIP.....NV.....EA..PLSREEFFE
44 ------SVDFCLPEH.ITPEIFLRDYW.QKKPLVIRNGLP.....EI.....IG..QFEPQDIIE
45 -VVTSSRAFGFMISP.CDVQTFFDKFY.QSNVLVVRRKQPtyfg.NL.....FS..TARLGELLE
46 --------PAQLLGG.LSPRDFMRTHW.QKKPLLIRQALSpedmrAL.....HF..PLSPDALIK
47 -----PDAPLTLLGG.MTPSAFMRDIW.HRKPLLIRQAVP.....EI.....VP..PVSREALFE
48 -VKTSRSMFEWLIYP.MKIEEFFEKNW.EKTPVHIKRNFP.....KYykll.MS..TPMLDKILR
49 --------------G.MPAQTFLTDYW.QKRPLLIRNAFP.....GL.....QS..PLQPEDLAG
50 -VVTASRAFGFMVSP.CDVQTFFDKFY.QSNVLVVHRKTPayyg.NL.....FS..TTRFSELLE
51 -----------LLGG.LAPADFMRRYW.QRKPLLIRQAIP.....GF.....KP..PASIAALRQ
52 --------PFCLPEN.ISPETFLRDYW.QKRPLLIRNGLP.....QI.....VG..LFEPEDIME
53 -----SKMKFCLPEH.ITPEIFLRDYW.QKKPLLIRNGLP.....EI.....VG..MFEPDDIIE
54 -----------LLGG.LAPADFMRRYW.QRKPLLIRQAIP.....GF.....KP..PVSIAALRQ
55 ---RAARLFEWLLAP.LPPDHFYRRLW.EREAVLVRRQDHsyye.GL.....FS..TSDLDWMLR
56 ---------------.-----------.------IRQAIP.....GF.....NG..LLSPDELAG
57 NFDSPSSLFESLISP.IKTETFFKEFW.EQKPLLIQRDDPalat.YY.....GS..LFKLTDLES
58 ---RAARLFEWLLAP.LPPDHFYRRLW.EREAVLVRRQDRsyye.GL.....FS..TADLDSMLR
59 ---------TPLLGA.LSPRRFMRRHW.QKRPLLIRQALP.....GV.....RP..PLDRGALFA
60 ---------------.-----------.------------.....--.....QD..PISPDELAG
61 ---------------.LDIAQFLKDYW.QQKPVVIKGAFP.....HF.....ED..PISADELAG
62 ---RAARLFEWLIAP.MPPDHFYRRLW.EREAVLVRRQDHtyyq.GL.....FS..TADLDSMLR
63 -----MNIPFCLPEN.ITPEIFLRDYW.QKKPLLIRNGLP.....QI.....VG..LFEPKDMME
64 --ERASKLLQWLISP.VPSRTFFSETW.EKKPILIQRKNP.....DYykgl.FS..TAEFDRILR
65 -VEEGRRVLQWILFP.VQTKVFFKDFW.EHTACLVQRSNP.....KYfqsm.IS..FKMLDEILI
66 -------------SG.LSLEGFLRDYYlPGTPVVITNSMA.....HW.....PA..RTKWNHLDY
67 -------------SG.LSLEGFLRDYYlPGTPVVITNSMA.....HW.....PA..RTKWNHLDY
68 ---SPQEFFQSLIRP.LDLQEFFQRFW.ERQPLVLHRSDAalag.YY.....GS..LFPLSGLRR
69 -------TFAWLIGPtISVDEFMRTHW.ERKPLLVQRSDRayya.GL.....LS..RAMIDEMLR
70 --------------S.LSLDEFNANY-.HSSPFILVNSDS.....NR.....WP..NWNFDLLFH
71 --------------S.LSLDEFNANY-.HSSPFILVNSDS.....NR.....WP..NWNFDLLFH
72 ---------------.-----------.------------.....--.....--..----EALFA
73 ----------ELLAP.VTLPEFFNSHW.PVEPLFIPATPG.....KL.....QD..IFALEQMQD
74 ---------------.--LQHFREQFLvPGRPVILKGVAD.....HWpc...MQ..KWSLEYIQE
75 ---------------.--LQHFREQFLvPGRPVILKGVAD.....HWpc...MQ..KWSLEYIQE
76 ---------------.--LQYFKQHFLvPGRPVILEGVAD.....HWpc...MK..KWSLQYIQE
77 ------------VRG.ISVEDFITKFEePNKPVLLEGCLD.....GWpa...IE..KWSRDYLTK
78 -RMRAASGVIERCER.LSRDAFFEQYYfQNRPVIITGAFD.....FWpa...CS..RWNWDYLRR
79 ---------THLIQP.LKQEEFLENNW.TKKAIAISNKGEk....DF.....TD..LFSWEKLNY
80 -VMEEERCTVERRAH.ITYSEFMQHYA.FLKPVILQGLTDns...KF.....RA..LCSRENLLA
81 -VMEEERCTVERRAH.ITYSEFMQHYA.LLKPVILQGLTDns...KF.....RA..LCSRENLLA
82 ---------------.-----------.------------.....--.....--..-----DIRS
83 -VAEEERCTVERRAD.LTYAEFVQQYA.FVRPVILQGLTDns...RF.....RA..LCSRDRLLA
84 -VAEEERCTVERRAD.LTYAEFVQQYA.FVRPVILQGLTDns...RF.....RA..LCSRDRLLA
85 ---------------.-----------.------------.....--.....--..---------
86 -------SLAWLLRS.LGVDAFLNEIW.ATRHHHIDRCRP.....GY.....FDglLPGPSAVDG
87 ---------------.-----------.------------.....--.....--..---------
88 --AVADNVERADALQ.LSVEEFVERYErPYKPVVLLNAQE.....GWsa...QE..KWTLERLKR
89 --AVADNVERADALQ.LSVEEFVERYErPYKPVVLLNAQE.....GWsa...QE..KWTLERLKR
90 ---------------.-----------.------------.....--.....--..---------
91 --AVADNVERADALQ.LSVEEFVERYErPYKPVVLLNAQE.....GWsa...QE..KWTLERLKR
92 --AVADNVERADALQ.LSVEEFVERYErPYKPVVLLNAQE.....GWsa...QE..KWTLERLKR
93 ----LDNVERVDAAQ.LTTEEFIERYEkPYKPVVIINATA.....GWpa...NE..KWTLERLKR
94 --AVSDNVERADALQ.LSVKEFVERYErPYKPVVLLNAQE.....GWsa...QE..KWTLERLKR
95 -------------SH.VSPAEFFERYVvGSRPLVLTDVAG.....DWpalhrWS..PADLRERFG
96 ---------------.-SLEYFGTRCYdTKQPAVLNGIID.....GW.....PA..MERWHDPNY
97 ----------ERRSC.ISLEAFIRDYFlCESPVILSGYID.....HW.....PA..RTKWKDIRY
98 ---------------.-----------.------------.....--.....--..---------
99 ---------------.-----------.------------.....--.....--..---------
100 ---------------.-----------.------------.....--.....--..---------
101 ---------------.-----------.------------.....--.....--..---------
102 --------------P.IDKKDFLENFF.EKKPCVFKKIYDd....DF.....IK..HSEIENIFN
103 ---------------.-----------.---PYVVRNADP.....DWacfr.QS..FAEWCEAFD
104 ---------------.-----------.------------.....--.....--..---------
105 ---------------.-----------.------------.....--.....--..---------
106 ---------RVDGNN.LTVEEFRRDFErPRIPVIITGLTD.....NWaa...KD..KWTVERLSK
107 ---------------.-----------.------------.....--.....--..---------
108 ---------RIHCKS.ISHDEFIARYEkPRIPVILTGCTD.....SWla...NQ..KWKLSSLAK
109 ---------------.---EDFLAQAL.HREHRHIPGALD.....-V.....AG..LMTFDDLNQ
110 ---------------.-----------.---PVVLRGVAR.....NWslvq.AG..LRSADEAMA
111 ---------------.-----------.----------AE.....TV.....AP..LLTFDALSE
112 --------------G.ISPKTFRQTYL.YQKPKLFKGAVR.....NL.....ES..-ASWKDINE
113 ---------------.-----------.------------.....--.....--..---------
114 ---------------.-----------.------------.....--.....--..---------
115 ---------------.-----------.------------.....--.....--..---------
116 ---------------.-----------.------------.....--.....--..---------
117 -------------SE.LSLIEFESRYLpNGIPVVISNALH.....DWp....--..--LFRLSRE
118 ---------------.-----------.------------.....--.....--..---------
119 ---------------.---------HW.NTRPLLVRAADRaa7raSV.....HD..LLSPADVDE
120 ---------------.----HFYRDWVcPNRPCIIRNALQ.....HW.....PA..LQKWSLPYF
121 ---------------.-----------.------------.....--.....--..---------
122 ---------------.-----------.------------.....--.....--..---------
123 ---------RVDGNN.LTVEEFRRDFErPRIPVIITGLTD.....NW.....AA..KDKW-----
124 ---------------.-----------.------------.....--.....--..---------
125 ---------------.-----------.------------.....--.....--..---------
126 ---------------.---QNFAKNHW.EKKPLVARNVKS.....GLlemtdAE..IFELLVAYS
127 ---------------.-----------.---PLVLEQFPL.....KWecfe.GS..LHDWCKRFD
128 ---------------.-----------.--TPLIVRRHSS.....NMpa...IE..KWSFPFLLQ
129 ---------------.-----------.------------.....--.....--..---------
130 ---------------.-----------.------------.....--.....--..---------
131 ---------------.-----------.------------.....--.....--..---------
132 ---------------.-----------.------------.....--.....--..---------
133 ---------------.-----------.---PLVLRGYAE.....DWpa8gqSS..AAALSYIEE
134 ---------------.-----------.------------.....--.....--..---------
135 ---------------.-----------.------------.....--.....--..---------
136 ---------------.-----------.------------.....--.....--..---------
137 ---------------.-----------.------------.....--.....--..---------
138 NFDSPSSLFESLISP.IKTETFFKEFW.EQKPLLIQRDDPalat.YY.....GS..LFKLTDLKS
139 ---------------.-----------.------------.....--.....--..---------
140 ---------------.-----------.------------.....--.....--..---------
141 ---------------.-----------.------------.....--.....--..---------
142 ---------------.-----------.------------.....--.....--..---------
143 ---------------.-----------.------------.....--.....--..---------
144 NFDSPSSFFESLISP.IKVETFFKEFW.EQKPLLIQRDDPvlak.YY.....QS..LFSLSDLKR
145 ---------------.-----------.------------.....--.....--..---------
146 ---------------.-----------.------------.....--.....--..---------
147 ---------------.-----------.------------.....--.....--..---------
60 70 80 90
| | | |
1 LE.....NVLAIYNNPVMVVGD.....AVIEESEGITD.....RFLVSPAEALEWYE.....KGA
2 LA.....MESEVDSRLV-SHQD.....GKWQVSHGPFE.....-------SYDHLGE.....TNW
3 LA.....MESEVDSRLV-SHQD.....GKWQVSHGPFE.....-------SYDHLGE.....TNW
4 LA.....MESEVDSRLV-SHQD.....GKWQVSHGPFE.....-------SYDHLGE.....TNW
5 LA.....MESEVDSRLV-SHQD.....GKWQVSHGPFE.....-------SYDHLGE.....TNW
6 LA.....MESEVDSRLV-SHQD.....GKWQVSHGPFE.....-------SYDHLGE.....TNW
7 LA.....MESEIDSRLV-SHQD.....GKWQVSHGPFE.....-------SYDHLGE.....SNW
8 LA.....MESEIDSRLV-SHQD.....GKWQVSHGPFE.....-------SYDHLGE.....SNW
9 LA.....MENEVDSRLV-SHED.....GRWHVSHGPFE.....-------SFDHLGE.....NNW
10 LA.....MENEVDSRLV-SHED.....GRWHVSHGPFE.....-------SFDHLGE.....NNW
11 LA.....MENEVDCRLV-SQKN.....GRWDVSHGPFE.....-------SYDHLGE.....KEW
12 LC.....SQGLYYGRDVNVCRCig...GKKKVLNKDGK.....AQFLQLRK--DFDQ.....KRA
13 LS.....LEEEVESRLIIEHGN.....HPWELRRGPFD.....-----EETYRNLPE.....RDW
14 LE.....NVLAIYNNPVMVVGD.....AVIEESEGITD.....RFLVSPAEALEWYE.....KGA
15 LA.....CEEGVLCRLVRHNRNt....DTWEVRHGPFQ.....-----EEEFPKLPD.....HDW
16 LA.....CEEGVLCRLVRHNRNt....DTWEVRHGPFQ.....-----EEEFPKLPD.....HDW
17 LA.....CEEGVLCRLVRHNRNt....DTWEVRHGPFQ.....-----EEEFPKLPD.....HDW
18 LS.....LEESVESRIVLEHGK.....TPWEMRRGPFQ.....-----EEDYQHLPE.....QDW
19 LA.....LEEEVESRLVIENGE.....RPWELRRGPFA.....-----EDEFSKLPE.....RDW
20 LS.....LEESVESRIVLEHGK.....TPWEMRRGPFQ.....-----EEDYQHLPE.....QDW
21 LA.....LEEEVESRLVIENGE.....RPWELRRGPFA.....-----EDEFSKLPE.....RDW
22 LA.....CEEGVLCRLVQHDRNt....DTWEVRHGPFQ.....-----EEEFPKLPD.....HDW
23 LC.....SRGMYYGRDVNVCRCvn...GKKKVLNKDGK.....AHFLQLRK--DFDQ.....KRA
24 LC.....SRGMYYGRDVNVCRCvn...GKKKVLNKDGK.....AHFLQLRK--DFDQ.....KRA
25 LC.....SRGMYYGRDVNVCRCvn...GKKKVLNKDGK.....AHFLQLRK--DFDQ.....KRA
26 LC.....KKGVYYGRDVNVCRSin...GKKKVLNKDGR.....AHFLQLRK--DFDQ.....KRA
27 LC.....SRGMYYGRDVNVCRCvn...GKKKVLNKDGK.....AHFLQLRK--DFDQ.....KRA
28 LC.....KKGVYYGRDVNVCRSis...GKKKVLNKDGR.....AHFLQLRK--DFDQ.....KRA
29 LC.....KKGVYYGRDVNVCRSis...GKKKVLNKDGR.....AHFLQLRK--DFDQ.....KRA
30 LC.....SQGLYYGRDVNVCRCig...GKKKVLNKDGK.....AQFLQLRK--DFDQ.....KRA
31 LA.....LEDEVESRIVLEHGA.....HPWELRRGPFN.....-----EDTFAELPE.....KDW
32 LA.....CEDGVLARLISHDRAt....DGWDVRTGPFQ.....-----ETDFPGLPA.....HDW
33 LA.....LEEEVESRLVIEHGE.....RPWELRRGPFA.....-----EDEFSKLPE.....REW
34 LC.....LEDDVISRLITETPQsspfnSEWNVTHGPLP.....-----EDIFETLPE.....NYW
35 LA.....MEEDVDSRYI-ARNG.....EEWDVRHGPLS.....--------FDNTPE.....DHW
36 LA.....CEDGVLARLISHDRAa....DDWTVRSGPFQ.....-----ETDFPGLPD.....HDW
37 LA.....ADYDAESRLI-THFR.....NKWQLAHGPFE.....-----PGALPAVSR.....KAW
38 LA.....ADYDAESRLI-THFR.....NKWQLEHGPFE.....-----PGSLPAVTR.....KAW
39 LA.....QNEDVTARLVKTFSD.....DDWKVFFSPLS.....-----EKDFQKLPE.....K-W
40 LA.....QNEDVTARLVKTFSD.....DNWKVFFSPLS.....-----EKDFQKLPE.....K-W
41 LA.....QRDDAESRLI-EYKK.....DKWHLERGPFR.....-----ASRFRRLAE.....TDW
42 KN.....HLEYGRNINIAQYKN.....GVRTTLNGQGR.....---AYPQIVKQHLH.....NMC
43 LA.....DQDEVEARLI-THFR.....NKWQLEHGPFA.....-----PDELPSLKQ.....RAW
44 LA.....QNEDVTARLVKTFSD.....DDWKVFFSPLS.....-----EKDFQQLPE.....K-W
45 KN.....HLEYGRNINIAQYKN.....GVRTTLNGQGR.....---AYPQIVKQHLH.....NMC
46 LA.....RREDVESRLI-AQTR.....GRWTFNHGPFN.....-----ERPLPSRKA.....RNW
47 LA.....DRDDVESRLVS-FFR.....NRWKLEHGPFS.....-----EDNLPSRKT.....GKW
48 ES.....YILFTKNIDITSYEN.....GVRETHNPIGR.....---AVPTVVWDYYM.....NGC
49 LA.....CEEGALARLIQHDRAr....DHYSVRHGPFE.....-----ESEFPGLPQ.....QDW
50 KH.....YLEYNMNINIAQYKD.....GIRTTLNGKGR.....---VYPQIVKQHLH.....NLC
51 LA.....RRDDVEARLI-WREQ.....GQWNMENGPFA.....-------RLPKAGE.....PDW
52 LA.....LEEEITARLI-KCEN.....EQWSVKTSPFA.....-----ESDLQDLPA.....Q-F
53 LA.....QQEDVTSRLIKQFSE.....DNWQLARSPLT.....-----AKDFKNLPA.....Q-W
54 MA.....RRDDVEARLI-WREQ.....GQWNMENGPFA.....-------RLPKAGE.....PDW
55 YE.....DVHFGQHLDAARYID.....GRRETLNPPGR.....---ALPAAAWSLYQ.....AGC
56 LA.....CEEDVQSRLV-SLKR.....GRWHVENGPFD.....-----EKRFAKLPE.....RDW
57 LC.....SRGMYYGRDVNVCRCvs...GKKKVLNKDGK.....AHFLQLRK--DFDQ.....KRA
58 YE.....DVQFGQHLDAARYVD.....GRRETLNPPGR.....---ALPAAAWSLYR.....AGC
59 LA.....GSEDVESRLI-VRQR.....DRWTLRSGPLP.....-----RRALPPVSQ.....AGW
60 LA.....MEEVIESRLV-TRFN.....NKWEAAHGPFE.....-------SYDHLGE.....ENW
61 LA.....CEEEITSRIV-VTQK.....DNWEVIQGPFE.....-------DYDNYGE.....THW
62 NE.....EVQFGQHLDAARYIN.....GRRETLNPPGR.....---ALPAAAWSLYQ.....AGC
63 LA.....LEEEITARLI-KCED.....EQWSVKNSPFT.....-----PHDLTKLPT.....K-W
64 EE.....DVQYGVNLDVTSYTN.....GRRETHNPPGR.....---ALPYNVWGFYK.....SGC
65 RH.....HLDFTVNVDVTTYKN.....GKRETLNPEGR.....---ALPPAVWGFYS.....DGC
66 LN.....AVAGNRTVPVEVGKN.....YLCSDWKQELV.....TFSKFLERMRTNKS.....SPM
67 LN.....AVAGNRTVPVEVGKN.....YLCSDWKQELV.....TFSKFLERMRTNKS.....SPM
68 LC.....ARGLQYGTDINTCRCvr...GQKRLLNRAGA.....VDFCLLER--DFLE.....KKA
69 TN.....NIEYTKNIDITSYRD.....GQRETHNPDGR.....---VLPPDLWHFYD.....AGC
70 RF.....PNVKFRQEAVSWDLQ.....KYSQYLHNNKD.....-----ENPLYLFDC.....KSD
71 RF.....PNVKFRQEAVSWDLQ.....KYSQYLHNNKD.....-----ENPLYLFDC.....KSD
72 LA.....DRDEVESRLV-THFR.....NRWKLENGPFA.....-----ADNLPTIKT.....KQW
73 LK.....NLISARQRKVRACLP.....DFDDEYSSIH-.....---LEPGDALKAYR.....NNM
74 IA.....GCRTVPVEVGSRYTDeews.QTLMTVNEFIS.....KYIVNEPRDVGYLA.....Q--
75 IA.....GCRTVPVEVGSRYTDeews.QTLMTVNEFIS.....KYIVNEPRDVGYLA.....Q--
76 IA.....GCRTVPVEVGSRYTDedws.QTLMTVDEFIQ.....KFILSEAKDVGYLA.....Q--
77 VV.....GDVEFAVGPVEMKLE.....KYFRYSDGARE.....-----ERPLYLFDP.....KFA
78 QC.....GDCEVEVQFGR--ES.....DANYEINQPRL.....TRMMRFADYVDLVEqrgptNDF
79 LL.....NFHQIKYPDVRLAFD.....GKVLEEKENRN.....--------FTQWCE.....KGA
80 SF.....GDNIVRLSTANTYSY.....QKVDLPFQEYV.....EQLLQPQDPASLGN.....D--
81 SF.....GDNIVRLSTANTYSY.....QKVDLPFQEYV.....EQLLQPQDPASLGN.....D--
82 HE.....RVSLPFSDFIRFCKQ.....HMRGKGNGSGVd....AKSADLNPMCEDYR.....PGQ
83 SF.....GDRVVRLSTANTYSY.....HKVDLPFQEYV.....EQLLHPQDPTSLGN.....D--
84 SF.....GDRVVRLSTANTYSY.....HKVDLPFQEYV.....EQLLHPQDPTSLGN.....D--
85 --.....---------------.....-----------.....--------------.....---
86 LL.....EQVRPDPAAVRLVKD.....GEDRDPAGYRRg....DGTLNAGGARDGLA.....DGY
87 --.....---------------.....-----------.....--------------.....---
88 KYrn6fkCGEDNDGYSVKMKMK.....YYIEYMESTRD.....--------------.....DSP
89 KYrn6fkCGEDNDGYSVKMKMK.....YYIEYMESTRD.....--------------.....DSP
90 --.....---------------.....-----------.....--------------.....--R
91 KYrn6fkCGEDNDGYSVKMKMK.....YYIEYMESTRD.....--------------.....DSP
92 KYrn6fkCGEDNDGYSVKMKMK.....YYIEYMESTRD.....--------------.....DSP
93 KYrn6fkCGEDNDGYSVKMKMK.....YYIDYMEGTRD.....--------------.....DSP
94 KYrn6fkCGEDNDGYSVKMKMK.....YYIEYMESTRD.....--------------.....DSP
95 HL.....DVEIQAERAVNPKYE.....QDKLKHRHNVR.....LGDFVDRVLAGGAT.....NDY
96 LL.....KVAGERTVPIEIGSQy....SSDDWSQKLMK.....FRDFLEQSICCEPS.....DSA
97 LE.....RIAGDRTVPV-----.....-----------.....--------------.....---
98 --.....---------------.....-----------.....--------------.....---
99 --.....---------------.....-----------.....--------------.....---
100 --.....---------------.....-----------.....--------------.....---
101 --.....---------------.....-----------.....--------------.....---
102 RS.....NLPSFEGIKLMYNGIi....DKTEYIESYNDlgtr.RYRYIYSKLYDYLN.....SGA
103 LA.....HPDCVPFEGCPVKGG.....NHPQWEWERTK.....VKMKMRDICTPTDT.....RWN
104 --.....---------------.....-----------.....--------------.....---
105 --.....---------------.....-----------.....--------------.....---
106 KY.....RNQNFKCGED-DNGN.....SVRMKMKYYHD.....YMLNNKDDSPLYIF.....DSS
107 --.....---------------.....-----------.....----------DTVG.....RKI
108 KYrn6fkVGEDNDGFSVKMKMK.....YYIE-------.....-------YLKHQKD.....DSP
109 IL.....ATHRLEPPRMRLSRD.....GETLLVGGYTTpv9tvWHRLHPAELHTRLT.....EGA
110 LL.....RAHDTGRPLQYSYGG.....PEIG-------.....--------SRPFYR.....DDC
111 LL.....STHQLEPPRLRLHRA.....GAPVPLDNYTEvg8vqRRLVRPEALYAQLR.....QGA
112 IY.....QRADPTAPLFHLRKK.....GAIVPKEEYVEsf8ktRYRFIKSVIYEHMK.....NGA
113 --.....---------------.....-----------.....--------------.....---
114 --.....---------------.....-----------.....--------------.....---
115 --.....---------------.....-----------.....--------------.....---
116 --.....---------------.....-----------.....--------------.....---
117 ES.....LVHFAELQGITRHGD.....YVKKTFSTERD.....FRSTSMADFIASLD.....SPA
118 --.....---------------.....-----------.....--------------.....---
119 LL.....GPRALRTPFFSLVQD.....GTPLPRSSYTR.....RAVAGNQQLADLPDtd9haGGA
120 RA.....TVGSTEVSVA-VTPD.....GYADAVRGDRFmm8rlPLSFVLDVLEGRAQ.....HPG
121 --.....---------------.....-----------.....--------------.....---
122 --.....---------------.....-----------.....--------------.....---
123 --.....---------------.....-----------.....--------------.....---
124 --.....---------------.....-----------.....--------------.....---
125 --.....---------------.....-----------.....--------------.....---
126 DR.....CREMNDPEGLKFFID.....GAKADPEEVLE.....LLPEKSDKSLLGYH.....KRM
127 KE.....ATCLPAFELMALADS.....STPQWERKRTKss8mqQFLRKYGVLDGDST.....HWA
128 EL.....HSRTFPVEIGTKYSDenws.QKLMTFKEFIR.....-------------N.....SEN
129 --.....---------------.....-----------.....--------------.....---
130 --.....---------------.....-----------.....--------------.....---
131 --.....---------------.....-----------.....--------------.....---
132 --.....---------------.....-----------.....--------------.....---
133 RY.....ARVPVTTCLLPAKER.....GRIFYNEAMNGf12htFIKMLLNEVDSPNP.....RGV
134 --.....---------------.....-----------.....----VLDVLEGRAQ.....HPG
135 --.....---------------.....-----------.....--------------.....---
136 --.....---------------.....-----------.....--------------.....---
137 --.....---------------.....-----------.....--------------.....---
138 LC.....SRGMYYGRDVNVCRCvn...GKKKVLNKDGK.....AHFLQLRK--DFDQ.....KRA
139 --.....---------------.....-----------.....--------------.....---
140 --.....----GEGRLANLYAS.....GWRFFEHNPDM.....--------------.....---
141 --.....------DRIASEHFD.....GPRVYLQDDVN.....--------------.....---
142 --.....---------------.....-----------.....--------------.....---
143 --.....---------------.....-----------.....--------------.....---
144 LC.....KKGVYYGRDVNVCRSis...GKKKVLNKDGR.....AHFLQLRK--DFDQ.....KRA
145 --.....---------------.....-----------.....--------------.....---
146 --.....---------------.....-----------.....--------------.....---
147 --.....---------------.....-----------.....--------------.....---
100 110 120 130
| | | |
1 ALEFDFT.....DLFIPQ.....VRRWIEKLK..AELRLPAGT..S.....SKA.....IVYAAK
2 SLLVQAV.....NHWHEP.....TAALMRPFR..E---LPDWR..I.....DDL.....MISFSV
3 SLLVQAV.....NHWHEP.....TAALMRPFR..E---LPDWR..I.....DDL.....MISFSV
4 SLLVQAV.....NHWHEP.....TAALMRPFR..E---LPDWR..I.....DDL.....MISFSV
5 SLLVQAV.....NHWHEP.....TAALMRPFR..E---LPDWR..I.....DDL.....MISFSV
6 SLLVQAV.....NHWHEP.....TAALMRPFR..E---LPDWR..I.....DDL.....MISFSV
7 SLLVQAV.....NHWHEP.....TAALMRPFR..A---LPDWR..I.....DDL.....MISFSV
8 SLLVQAV.....NHWHEP.....TAALMRPFR..A---LPDWR..I.....DDL.....MISFSV
9 SLLVQAV.....DHWHEP.....AAALMRPFR..P---LSDWR..M.....DDL.....MISFSV
10 SLLVQAV.....DHWHEP.....AAALMRPFR..P---LSDWR..M.....DDL.....MISFSV
11 SLLVQAV.....NHWHRP.....SAALMQPFR..V---LSDWR..I.....DDL.....MVSFSV
12 TIQFHQP.....QRFKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYM.....---TPA
13 TLLVQAV.....DQFVPE.....VAELLENFR..F---LPSWR..I.....DDV.....MISYAA
14 ALEFDFT.....DLFIPQ.....VRRWIEKLK..AELRLPAGT..S.....SKA.....IVYAAK
15 TLLVQDV.....DKWDQD.....VRALLEHFR..F---LPRWR..I.....DDI.....MISFAA
16 TLLVQDV.....DKWDQD.....VRALLEHFR..F---LPRWR..I.....DDI.....MISFAA
17 TLLVQDV.....DKWDQD.....VRALLEHFR..F---LPRWR..I.....DDI.....MISFAA
18 TLLVQAV.....DQFVPE.....VAQLLEQFR..F---LPSWR..I.....DDV.....MISYAA
19 TLLVQAV.....DQFVPE.....VSELLENFR..F---LPSWR..I.....DDV.....MISYAA
20 TLLVQAV.....DQFVPE.....VAQLLEQFR..F---LPSWR..I.....DDV.....MISYAA
21 TLLVQAV.....DQFVPE.....VSELLENFR..F---LPSWR..I.....DDV.....MISYAA
22 TLLVQDV.....DKWDQD.....VRALLEHFR..F---LPRWR..I.....DDI.....MISFAA
23 TIQFHQP.....QRFKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYI.....---TPA
24 TIQFHQP.....QRFKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYI.....---TPA
25 TIQFHQP.....QRFKDE.....LWRIQEKLE..CYFSSLVGS..N.....VYI.....---TPA
26 TIQFHQP.....QRYKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYM.....---TPA
27 TIQFHQP.....QRFKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYI.....---TPA
28 TIQFHQP.....QRYKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYM.....---TPA
29 TIQFHQP.....QRYKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYM.....---TPA
30 TIQFHQP.....QRFKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYM.....---IPA
31 TLLVQAV.....DQFVPE.....VAELLENFR..F---LPSWR..I.....DDV.....MISFAA
32 TLLVQDV.....DKWDAD.....VRALLEHFR..F---LPRWR..I.....DDI.....MISFAA
33 TLLVQAV.....DQFVPE.....VSELLENFR..F---LPSWR..V.....DDV.....MISFAA
34 SLLVQHV.....DQLSPE.....VNQLLNLFR..F---IPNWR..L.....DDV.....MISYAP
35 SFIVQAA.....NHWHEG.....AARLVTPFR..Q---LPNWL..F.....DDL.....MISYST
36 TLLVQDV.....DKWDAD.....VRALLEQFR..F---LPRWR..I.....DDI.....MISFAA
37 SLLVQGL.....DLHVDA.....ARALLDRFR..F---IPDAR..L.....DDL.....MISYAT
38 TLLVQGL.....DLHVDA.....ARALLDRFR..F---IPDAR..L.....DDL.....MISYAT
39 SVLVQNL.....EQWSPE.....LGQLWNKFG..F---IPQWQ..R.....DDI.....MVSYAP
40 SVLVQNL.....EQWSPE.....LGQLWNKFG..F---IPQWQ..R.....DDI.....MVSYAP
41 TLLVQGV.....NHHLPH.....IDDILWRFN..F---IPYAR..L.....DDL.....MISYAP
42 SVQLVNP.....QTYDDR.....IWYLCEVIQ..EQFGCFVGA..N.....TYL.....---TPA
43 TLLVQGV.....DLYDDR.....ARALLDRFR..F---VPDAR..L.....DDL.....MISYAT
44 SVLVQNL.....EQWSPE.....LGQLWNKFG..F---IPQWQ..R.....DDI.....MVSYAP
45 SVQLVNP.....QTYDDR.....IWYLCEVIQ..EQFGCFVGA..N.....TYL.....---TPA
46 TLLVQGV.....NLVEPA.....VDALMQRFR..F---IPDAR..L.....DDV.....MISFAT
47 SLLVQGV.....NLHDRA.....AAELMSQFR..F---VPDAR..L.....DDV.....MISYAT
48 SVRMLNP.....QTYIPK.....LHSLNATLQ..EFFGCFIGA..N.....SYL.....---TPP
49 TLLVQDV.....DKWDAD.....VAALLPAFS..F---LPRWR..I.....DDI.....MVSFAA
50 SVQLVNP.....QTFDDR.....IWYLCEILQ..EQFGCFVGA..N.....TYL.....---TPA
51 TLLVQSV.....DLHHDA.....VSALLQQFR..F---IPDAR..L.....DDI.....MISVAG
52 SVMVQNL.....EQWSPE.....LGALWQAFS..F---LPQWQ..R.....DDI.....MVSCSP
53 SVLVQNL.....EQWSPE.....LGQLWHAFG..F---IPQWQ..R.....DDI.....MVSYAP
54 TLLVQSV.....DLHHDA.....VSALLQQFR..F---IPDAR..L.....DDI.....MISVAG
55 SLRLLCP.....QAFSPT.....VWQFLAVLQ..EQFGSMAGS..N.....VYL.....---TPP
56 TLLVQGV.....NHHLPE.....AAELLQQFA..F---IPYAR..L.....DDL.....MVSFAP
57 TIQFHQP.....QRFKDE.....LWRIQEKLE..CYFGSLVGS..N.....VYI.....---TPA
58 SLRLLCP.....QAFSPT.....VWQFLAVLQ..EQFGSMAGS..N.....VYL.....---TPP
59 TLLVQGL.....DLHVPA.....ARDLLSMFR..F---VPEAR..L.....DDL.....MLSWAS
60 TVLVQAC.....NHWAPE.....VNELALPFQ..F---IPGWR..F.....DDV.....MVSFST
61 QLLVQAV.....NHWYPD.....SQPLVEAFR..F---LPDWR..F.....DDL.....MVSFAT
62 SLRLLCP.....QAFSTT.....VWQFLAVLQ..EQFGSMAGS..N.....VYL.....---TPP
63 SLMIQNL.....EQWSSE.....LGALWQAFN..F---IPQWQ..R.....DDI.....MVSCSP
64 SLRLLNP.....QAFSST.....VWNILSILQ..ENFGSMAGA..N.....IYL.....---TPP
65 SIRLLNP.....STYLIR.....LRQVCTVLQ..EFFHCKVGA..N.....LYL.....---TPP
66 EPTYLAQ.....HPLFDQ.....INELRDDIC..IPDYCFVGG..Gel...QSL.....NAWFGP
67 EPTYLAQ.....HPLFDQ.....INELRDDIC..IPDYCFVGG..Gel...QSL.....NAWFGP
68 TIQFHQP.....QRFQDE.....LWRIQERLE..CFFGCLVGS..N.....VYI.....---TPA
69 SVRMLNP.....QTYLRS.....VYELNVKLQ..EYFHCMTGA..N.....FYL.....---TPP
70 AMKVLKQ.....EYKVPE.....IFQDDLFTV..FNSKQFNCR..P.....DHA.....WIIMGS
71 AMKVLKQ.....EYKVPE.....IFQDDLFTV..FNSKQFNCR..P.....DHA.....WIIMGS
72 TLLVQGV.....NLHDAA.....AADLMGQFR..F---VPDAR..L.....DDL.....MISYAT
73 TLVFDSM.....QSQDST.....IADMLGNVR..ADLGLVTGG..Aen6ckARS.....IAYATP
74 -------.....HQLFDQ.....IPELKQDIS..IPDYCSLGD..Geeee.ITI.....NAWFGP
75 -------.....HQLFDQ.....IPELKQDIS..IPDYCSLGD..Geeee.ITI.....NAWFGP
76 -------.....HQLFDQ.....IPELKRDIS..IPDYCCLGN..Geeee.ITI.....NAWFGP
77 EKVPVLD.....SEYDVP.....VYFREDLFG..V---LGNER..P.....DYR.....WIIIGP
78 YMTANNT.....SRNRAA.....LAALWSDVP..PIDAYLDAA..Sp....DTG.....FFWMGP
79 TLILDQI.....HRRIPE.....VAIFTSKLS..YELGYPTQV..N.....AYC.....---SWS
80 TLYFFGD.....NNFTEW.....ASLFQHYSP..PPFRLLGTT..P.....AYS.....-FGIAG
81 TLYFFGD.....NNFTEW.....ASLFQHYSP..PPFRLLGTT..P.....AYS.....-FGIAG
82 IYLAQFP.....ILNDEKeekvlLKILRQDIQ..TPTFLDAKS..L.....SSI.....NFWMNS
83 TLYFFGD.....NNFTEW.....ASLFRHYSP..PPFGLLGTA..P.....AYS.....-FGIAG
84 TLYFFGD.....NNFTEW.....ASLFRHYSP..PPFGLLGTA..P.....AYS.....-FGIAG
85 -------.....------.....-WNWINKQQ..GKRGWGQLT..S.....NLL.....--LIGM
86 TLVLNGL.....ERYLRT.....VASLSHAIE..VELNFPTRV..N.....AYV.....---TPP
87 -------.....------.....NWNWINKQQ..GKRGWGQLT..S.....NLL.....--LIGM
88 LYIFDSS.....YGEHPK.....RRKLLEDYK..VPKFFTDDL..F.....QYAge9yrWFVMGP
89 LYIFDSS.....YGEHPK.....RRKLLEDYK..VPKFFTDDL..F.....QYAge9yrWFVMGP
90 LYLQQTL.....NDTVGRki9gfNWNWINKQQ..AKHGWGQLT..S.....NLL.....--LIGM
91 LYIFDSS.....YGEHPK.....RRKLLEDYK..VPKFFTDDL..F.....QYAge9yrWFVMGP
92 LYIFDSS.....YGEHPK.....RRKLLEDYK..VPKFFTDDL..F.....QYAge9yrWFVMGP
93 LYIFDSS.....YGEHPK.....RKKILEDYE..VPKYFRDDL..Fqf9rpPYR.....WFVMGP
94 LYIFDSS.....YGEHPK.....RRKLLEDYK..VPKFFTDDL..F.....QYAge9yrWFVMGP
95 YLTANNE.....ILRRPE.....FAPLLADIGtlPLFCDPAQL..A.....QRS.....SFWFGP
96 GKQPPAYlaq..HDLFDQ.....IPALRADIA..IPDYIGRTD..Aq....PRI.....KAWLGP
97 -------.....-----E.....IKELREDIM..VPEYCNAGGgeL.....QKL.....NAWFGP
98 -------.....------iv8gfNWNWINKQQ..GKRGWGQLT..S.....NLL.....--LIGM
99 -------.....------ki9gfNWNWINKQQ..GKRGWGQLT..S.....NLL.....--LIGM
100 -------.....------iv8gfNWNWINKQQ..GKRGWGQLT..S.....NLL.....--LIGM
101 -------.....------iv8gfNWNWINKQQ..AKHGWGQLT..S.....NLL.....--LIGM
102 TLVANGIin...ETKIDQ.....LAKACSSFT..DSHPF---S..S.....LYL.....--SYG-
103 SFSYRNI.....ALLPEP.....CRRGINFAC..F---GFPEV..E.....QDV.....TFWIGS
104 VLDFLGF.....N-----.....-WNWINKQQ..AQRNWGQLT..S.....NLL.....--LIGM
105 -------.....------ki9gfNWNWINKQQ..GKRGWGQLT..S.....NLL.....--LIGX
106 FAERRKT.....KKLSEDys...VPKFFEDDL..FHYADDKKR..P.....PHR.....WFVMGP
107 VVDFLGF.....------.....NWNWINKQQ..AKRNWGPLT..S.....NLL.....--LIGM
108 LYIFDGS.....YGEHPK.....KRKLLDDYH..PPSFFQDDL..Fky9rpPYR.....WIVIGP
109 SLALDSV.....DELHPP.....IARLCEAIE..RELHTRVQA..N.....LYA.....---SWS
110 SALNFQVqrgsvSTLLDA.....IAAHRDDPQ..PPTYYLASL..P.....VDAn22qpSIWIG-
111 SLVLDGI.....DRIHPP.....IRAAADDLM..RLVHERVQV..N.....LYL.....---IWG
112 SLVYNHInn...EPFSDH.....IARQVARFA..G---AHTIV..S.....GYL.....---AFG
113 -----FV.....SLFEDK.....TDLFQDVKW..SDFGFPGRN..G.....QES.....TLWIGS
114 -----FV.....SLFEDK.....TDLFQDVKW..SDFGFPGRN..G.....QES.....TLWIGS
115 ------V.....TLFEDK.....TDVFQEVMW..SDFGFPGRN..G.....QES.....TLWIGS
116 ------V.....TLFEDK.....TDVFQEVVW..SDFGFPGRN..G.....QES.....TLWIGS
117 VKGADGE.....PPAYMGnnil.PAALMEQIQ..YPPYFDASL..F.....IPP.....RIWIGP
118 -------.....-----T.....IDTWLPGLR..EHNDLGFGA..L.....QPLa....SIWIG-
119 TIVLQAL.....HRTWPA.....LQTFCSQLA..ADLGHQCQV..N.....VYV.....---TPP
120 VLYVQKQ.....CSNLPSelpqlLPDLESHVP..WASEALGKM..P.....DAV.....NFWLGE
121 -------.....------.....---------..----ALNEL..N.....PRV.....SIWIG-
122 -------.....------.....---------..---------..-.....PLA.....SIWIG-
123 TVERRKT.....KKLSEDys...VPKFFEDDL..FHYADDKKR..P.....PHR.....WFVMGP
124 -------.....------.....---------..---------..-.....PLA.....SIWIG-
125 -LASLPV.....DDYLPG.....LRAGNDLDM..R----ASGS..N.....VQP.....SIWIG-
126 NAQFPDY.....CLVCDEl11hlLQDFTDDLF..RHVGFPNRF..S.....EIG.....LYLGNY
127 AYQYKKA.....DEVPLS.....CRSGIGFSS..F--GFPDIG..N.....DYR.....-FWLGS
128 ERLYLAQ.....HRLFDQ.....VPHLKRDVI..IPDVCFGES..Snpen.VDM.....NMWIGP
129 -------.....------.....---------..---------..-.....---.....GIWLG-
130 -------.....AQLVPD.....LPSMFEDVRw.ADFGFEGRD..G.....GES.....TLWIGS
131 -------.....------.....-EVLKEDIQ..EPTFLRGKP..F.....SSI.....NIWMNR
132 -------.....------.....---CLPDFS..VENRLTFGVd.N.....PAA.....SIWLG-
133 YMPSTDA.....DKWFPGvvgen---------..-NAGLDGLD..P.....IKL.....-IWIG-
134 VLYVQKQ.....CSNLPSelpqlLPDLESHVP..WASEALGKM..P.....DAV.....NFWLGE
135 -------.....------.....---LLEKYQ..QPDWELPGH..T.....AAL.....SFGIAG
136 -----FV.....SLFEDK.....TDLFQDVKW..SDFGFPGRN..G.....QES.....TLWIGS
137 -------.....------.....---LLDKYK..QPEWKLPGH..T.....AAL.....SFGIAG
138 TIQFHQP.....QRFKDE.....LWRIQEKLE..CYFG-----..-.....---.....------
139 -------.....------.....---------..---------..-.....---.....------
140 ---LQDF.....NEPIPA.....IGDLLQGIP..EKLFKPL--..-.....--L.....WIFIGA
141 -------.....-NF---.....-PALKAYYR..EPQYLARHN..L.....KRT.....KLWVSG
142 ------I.....ADLPPN.....LQAALAPPH..VVLNAGKGD..V.....YGG.....SLWMGL
143 ---LQGV.....SLYIAQcs...IAELPQALQ..EDIPTPEIV..Vha7diYGS.....SIWLGI
144 TIQFHQP.....QR----.....---------..---------..-.....---.....------
145 -------.....------.....-DDWLNAYV..IDCESDDFR..F.....AYL.....----GS
146 -------.....------.....---WEEAVK..LEQALGAVV..T.....IDA.....IGSFG-
147 -------.....------.....---------..---------..-.....---.....------
140 150 160 170 180 190
| | | | | |
1 NGGGFKAHFDAYT..NLIFQIQGEKTWKLAKN.ENVSNPMQHYD.L.....SEA.PYYPDDLQSY
2 PGGGVGPHLDQYD..VFIIQGTGRRRWRVGEK.LQMKQHCPHPD.L.....LQV.----------
3 PGGGVGPHLDQYD..VFIIQGTGRRRWRVGEK.LQMKQHCPHPD.L.....LQV.----------
4 PGGGVGPHLDQYD..VFIIQGTGRRRWRVGEK.LQMKQHCPHPD.L.....LQV.----------
5 PGGGVGPHLDQYD..VFIIQGTGRRRWRVGEK.LQMKQHCPHPD.L.....LQV.----------
6 PGGGVGPHLDQYD..VFIIQGTGRRRWRVGEK.LQMKQHCPHPD.L.....LQV.----------
7 PGGGVGPHLDQYD..VFIIQGTGRRRWRVGEK.LQMRQHCPHPD.L.....LQV.----------
8 PGGGVGPHLDQYD..VFIIQGTGRRRWRVGEK.LQMRQHCPHPD.L.....LQV.----------
9 PGGGVGPHFDQYD..VFIIQGSGRRRWRVGEK.TEMKQHCPHPD.L.....LQV.----------
10 PGGGVGPHFDQYD..VFIIQGSGRRRWRVGEK.TEMKQHCPHPD.L.....LQV.----------
11 PGGGVGPHLDQYD..VFIIQGMGRRRWRVGEK.LPMEQRCPHPD.L.....LQV.----------
12 GSQGLPPHYDDVE..VFILQLEGRKRWRLYSP.T---VPLAREY.S.....VEP.E---------
13 PGGGVGPHYDNYD..VFLLQGYGKRRWRIGQM.CDSDSPLL---.-.....---.---------K
14 NGGGFKAHFDAYT..NLIFQIQGEKTWKLAKN.ENVSNPMQHYD.L.....SEA.PYYPDDLQSY
15 THGSVGAHVDQYD..VFLLQGQGHRHWHIDAS.VAMGRKAPPLD.F.....RN-.----------
16 THGSVGAHVDQYD..VFLLQGQGHRHWHIDAS.VAMGRKAPPLD.F.....RN-.----------
17 THGSVGAHVDQYD..VFLLQGQGHRHWHIDAS.VAMGRKAPPLD.F.....RN-.----------
18 PGGGVGPHFDNYD..VFLLQGHGRRRWKVGQM.CSSDSPLR---.-.....---.---------E
19 PGGSVGPHFDNYD..VFLLQGHGKRHWQIGQM.CDAESPLL---.-.....---.---------Q
20 PGGGVGPHFDNYD..VFLLQGHGRRRWKVGQM.CSSDSPLR---.-.....---.---------E
21 PGGGVGPHFDNYD..VFLLQGHGKRHWQIGQM.CDAESPLL---.-.....---.---------Q
22 THGSVGAHVDQYD..VFLLQGQGHRRWHIDAS.VAMGRKAPSLD.F.....RN-.----------
23 GSQGLPPHYDDVE..VFILQLEGEKHWRLYHP.T---VPLAREY.S.....VEA.E---------
24 GSQGLPPHYDDVE..VFILQLEGEKHWRLYHP.T---VPLAREY.S.....VEA.E---------
25 GSQGLPPHYDDVE..VFILQLEGEKHWRLYHP.T---VPLAREY.S.....VEA.E---------
26 GSQGLPPHYDDVE..VFILQLEGTKHWRLYSP.T---VPLAHEY.S.....VES.E---------
27 GSQGLPPHYDDVE..VFILQLEGEKHWRLYHP.T---VPLAREY.S.....VEA.E---------
28 GSQGLPPHYDDVE..VFILQLEGTKHWRLYSP.T---VPLAHEY.S.....VES.E---------
29 GSQGLPPHYDDVE..VFILQLEGTKHWRLYSP.T---VPLAHEY.S.....VES.E---------
30 VSQGLPPHYNDVE..VFVLQLEGKKRWRLYSP.T---VPLAREY.S.....VEP.E---------
31 PGGSVGPHFDNYD..VFLLQGHGQRNWKIGQM.CSSDSPLL---.-.....---.---------E
32 TGGSVGAHVDHYD..VFLLQGQGHRRWQIDAR.TVQGRKATPL-.-.....---.------AFRD
33 PGGSVGPHFDNYD..VFLLQGHGKRNWKIGQM.CDSESPLL---.-.....---.---------Q
34 DKGGVGPHFDYYD..VFLLQGHGQRRWRLGQQ.CTSKSPML---.-.....---.---------A
35 PSGGVGPHIDQYD..VFIIQGSGKRHWRVGPKkDDYEEELRHPA.L.....RQ-.----------
36 TGGSVGAHVDHYD..VFLLQGLGHRRWQVDAR.SSQGRKPTPM-.-.....---.------AFRD
37 DGGGVGPHFDSYD..VFLLQVEGRRRWRIGAQ.KDLSLL-----.-.....---.---------P
38 DGGGVGAHFDSYD..VFLLQVEGRRRWRVGAQ.KDLS-------.-.....---.-------LQP
39 KGGSVGKHYDEYD..VFLVQGYGHRRWQVGKW.CDASTEFK---.-.....---.---------P
40 KGGSVGKHYDEYD..VFLVQGYGHRRWQVGKW.CDASTEFK---.-.....---.---------P
41 PGGTVGPHFDAYD..VFLLQVGGKKRWQISSQ.HDDDFI-----.-.....---.---------E
42 GSSGFAPHWDEID..AFLLQVEGRKYWRVWAP.ESAEEELPLE-.-.....---.-------SSD
43 DGGGVGPHFDSYD..VFLLQVKGKRRWRISAQ.KDLT-------.-.....---.-------LQA
44 KGGSVGKHYDEYD..VFLVQGYGHRRWQVGKW.CDASTEFK---.-.....---.---------P
45 GSSGFAPHWDEID..AFLLQVEGRKYWRVWAP.ESAEEELPLE-.-.....---.-------SSD
46 DGGGVGPHFDSYD..VFLLQAHGRRRWRISSQ.NDLTLV-----.-.....---.---------P
47 DGGGVGPHFDSYD..VFLLQVSGRRRWRISSQ.TKLD-------.-.....---.-------LIP
48 NSQGFAPHYDDIE..AFILQIEGKKRWRLYKP.RNQNEYLPRY-.-.....---.-------SSE
49 PGGSVGAHVDQYD..VFLLQAQGHRRWQIDAR.PNPPQGFR---.-.....---.---------A
50 GSSGFAPHWDEID..AFLLQVEGRKYWRVWAP.ESAEEELPLE-.-.....---.-------SSG
51 DGGGVGPHFDSYD..VFLLQASGRRRWRYGRQ.KDLS-------.-.....---.-------LQP
52 KGGTVGKHYDEYD..VFLVQGYGQRRWQLGKW.CDPSTEFK---.-.....---.---------P
53 AGGSVGRHYDEYD..VFLVQGYGHRRWQLGKW.CDPSTEFK---.-.....---.---------A
54 DGGGVGPHFDSYD..VFLLQASGRRRWRYGRQ.KDLS-------.-.....---.-------LQP
55 NSQGFAPHYDDIE..AFVLQLEGRKLWRVYRP.RDPSEELALT-.-.....---.-------SSP
56 DQGGVGPHFDSYD..VFLLQGEGQRLWRISEQ.DDLALV-----.-.....---.---------E
57 GSQGLPPHYDDVE..VFILQLEGEKHWRLYHP.T---VPLAREY.S.....VEA.E---------
58 DSQGFAPHYDDIE..AFVLQLEGRKLWRVYRP.RDPSEELALT-.-.....---.-------SSP
59 DGGGVGPHVDSYD..VFLLQVQGRRRWRIAPP.GD---------.-.....---.-----DTLRP
60 PHGGVGPHIDNYD..VFITQGKGKRHWRVGDA.KPLNEFAAHAA.L.....LHC.----------
61 PNGGVGPHIDNYD..VFIIQGEGQRRWTVGDN.T----------.-.....---.---PQQCRGG
62 NSQGFAPHYDDIE..AFVLQLEGRKLWRVYRP.RAPTEELALT-.-.....---.-------SSP
63 KSGTVGKHYDEYD..VFLVQGFGTRRWQLGKW.CDRSTEFK---.-.....---.---------P
64 GTQGFAPHYDDIE..AFVVQLEGKKHWRVYNP.RVEDEVLPVF-.-.....---.-------SSP
65 NSQGFAPHYDDIE..AFVIQVEGRKRWLLYEP.PKKADQLARI-.-.....---.-------SSG
66 AGTVTPLHHDPHH..NILAQVVGKKYIRLYPS.FLQDELYPYSE.T.....MLC.NSSQVDLDNI
67 AGTVTPLHHDPHH..NILAQVVGKKYIRLYPS.FLQDELYPYSE.T.....MLC.NSSQVDLDNI
68 GAQGLPPHYDDVE..VLILQLEGQKHWRLYEP.T---VPLAREY.S.....LEP.E---------
69 GSQGFAPHYDDIE..AFVLQIEGRKRWRLYGP.RQPQEVLARV-.-.....---.-------SSE
70 ARSGSTFHKDPNStsAWNAAIQGRKLWVMLPP.HMTP-PGVGTD.E.....EES.EVTSPVSVAE
71 ARSGSTFHKDPNStsAWNAAIQGRKLWVMLPP.HMTP-PGVGTD.E.....EES.EVTSPVSVAE
72 DGGGVGPHFDSYD..VFLLQVSGRRRWRISSQ.TKLDLV-----.-.....---.---------P
73 AGCGTRLHFDANA..NFIIQIKGTKTWRLAPN.ESVEFPTERFT.T.....GSE.E-MPAALEKQ
74 QGTISPLHQDPQQ..NFLVQVMGRKYIRLYSP.QESGALYPHDT.H.....LLH.NTSQVDVENP
75 QGTISPLHQDPQQ..NFLVQVMGRKYIRLYSP.QESGALYPHDT.H.....LLH.NTSQVDVENP
76 QGTISPLHQDPQQ..NFLVQVLGRKYIRLYSP.QESEAVYPHET.H.....ILH.NTSQVDVENP
77 AGSGSSFHIDPNStsAWNAVITGSKKWVLFPP.DVVP-PGVHPS.P.....DGA.EVACPVSIIE
78 AGTKTPFHHDLTN..NFMAQVIGRKHIKLVPL.SDTPYMANHL-.-.....--H.CYSRVDGGAI
79 SKKGFSPHYDTHD..VFILQVEGNKQWYVYND.T-FKYPLPNQ-.-.....---.----------
80 AGSGVPFHWHGPG..-FSEVIYGRKRWFLYPP.EKTPEFHPNKT.T.....LAW.---------L
81 AGSGVPFHWHGPG..-FSEVIYGRKRWFLYPP.EKTPEFHPNKT.T.....LAW.---------L
82 AEARSSTHYDPHH..NLLCVVSGRKKVVLWPP.SASPSLYPMPI.Y.....GEAsNHSSVGLENP
83 AGSGVPFHWHGPG..-YSEVIYGRKRWFLYPP.EKTPEFHPNKT.T.....LAW.---------L
84 AGSGVPFHWHGPG..-YSEVIYGRKRWFLYPP.EKTPEFHPNKT.T.....LAW.---------L
85 EGNVTPAHYDEQQ..NFFAQIKGYKRCILFPP.DQFECLYPYP-.-.....--V.HHPCDRQSQV
86 HSTGFVPHYDPHD..VLVLQIEGCKTWRVSDE.P----------.-.....---.---PVPPQQI
87 EGNVTPAHYDEQQ..NFFAQIKGHKRCILFPP.DQFECLYPYP-.-.....--V.HHPCDRQSQV
88 PRSGTGIHIDPLGtsAWNALVQGHKRWCLFPT.STPRELIKVTR.D.....EGG.NQQDEAITWF
89 PRSGTGIHIDPLGtsAWNALVQGHKRWCLFPT.STPRELIKVTR.D.....EGG.NQQDEAITWF
90 EGNVTPAHYDEQQ..NFFAQIKGYKRCILFPP.EQFECLYPYP-.-.....--V.HHPCDRQSQV
91 PRSGTGIHIDPLGtsAWNALVQGHKRWCLFPT.STPRELIKVTR.D.....EGG.NQQDEAITWF
92 PRSGTGIHIDPLGtsAWNALVQGHKRWCLFPT.STPRELIKVTR.D.....EGG.NQQDEAITWF
93 PRSGTGIHIDPLGtsAWNSLVHGHKRWCLFPT.NTPRELIKVTR.D.....EGG.NQQDEAITWF
94 PRSGTGIHIDPLGtsAWNALVQGHKRWCLFPT.NTPRELIKVTR.E.....EGG.NQQDEAITWF
95 AGTVTPLHHDTLM..LLHTQVVGRKRWRFISP.LETPRLYNH--.-.....---.---DGVFSAI
96 KGTVSPLHTDPCH..NLLCQVFGAKLIILARP.EDTERLYPHDH.F.....ILN.NTSQVDARRP
97 EGTVTPLHHDLYH..NLFAQVLGRKYFRLYSA.SISNDLYPHRE.T.....MLS.NISQVDLDNI
98 EGNVTPAHYDEQQ..NFFAQIKGYKRCILFPP.DQFECLYPYP-.-.....--V.HHPCDRQSQV
99 EGNVTPAHYDEQQ..NFFAQIKGYKRCILFPP.DQFECLYPYP-.-.....--V.HHPCDRQSQV
100 EGNVTPAHYDEQQ..NFFAQIKGYKRCILFPP.DQFECLYPYP-.-.....--V.HHPCDRQSQV
101 EGNVTPAHYDEQQ..NFFGQIKGYKRCILFPP.EQFECLYPYP-.-.....--V.HHPCDRQSQV
102 EKSSFKPHWDSRD..IFAIQLSGKKRWIIYKP.SFPDPVYLH--.-.....---.-------QSK
103 AQAHTPCHYDTYGc.NVVVQVFGRKSWILLPP.DAKLTPVRVPF.E.....ESS.VYCEENFYSP
104 EGNVTPAHYDEQQ..NFFAQIKGHKRCILFPP.DQFECLYPYP-.-.....--V.HHPCDRQSQV
105 EGNVTPAHYDEQQ..NFFAQIKGYKRCILFPP.DQFECLYPYP-.-.....--V.HHPCDRQSQV
106 ARSGTAIHIDPLGtsAWNSLLQGHKRWVLIPP.IAPRDLVKPMA.H.....EKG.KHPDEGITWF
107 EGNVTPAHYDEQQ..NFFAQIKGHKRCILFPP.EQFDCLYPYP-.-.....--V.HHPCDRQSQV
108 ARSGTGIHIDPLGtsAWNALISGHKRWMMFPT.ETPKHLLEVSK.Q.....DGQ.HQSGEGIQWF
109 ATEGFGVHWDDHD..TVIVQLDGAKRWRIYGT.T---RPFPLY-.-.....---.---------R
110 NRVIASCHYDALD..NLACCAVGQRRFTLFPP.EQVANLYPGP-.-.....LDP.TPGGQVVSMV
111 DSHGFNTHWDDHD..TFIVQVAGTKHWQVHGQ.GTRPYPMK---.-.....---.---------E
112 SDESYKNHWDPRD..VYAIQLFGKKRWQLTAP.D---FPMPLY-.-.....---.-------MQQ
113 LGAHTPCHLDSYGc.NLVFQVQGRKRWHLFPP.EDTPFLYPTRI.P.....YEE.---SSVFSKI
114 LGAHTPCHLDSYGc.NLVFQVQGRKRWHLFPP.EDTPFLYPTRI.P.....YEE.---SSVFSKI
115 LGAHTPCHLDSYGc.NLVFQVQGRKRWHLFPP.EDTPFLYPTRI.P.....YEE.---SSVFSKI
116 FGAHTPCHLDSYGc.NLVFQVQGRKRWHLFPP.EDTPFLYPTRI.P.....YEE.---SSVFSKI
117 KGTLTPLHRDDTD..NLFAQVWGQKKFTLAAP.HHREALGTWST.A.....PE-.--GGLDGCDF
118 NRTRIPAHQDVPD..NIACVVAGRRRATLFPP.EQLQNLYIGP-.-.....LDR.TPAGQAISLV
119 GAQGFKPHHDTHD..VVVLQVDGRKHWTIHPP.A---VELPLK-.-.....---.-----SQPST
120 AAAVTSLHKDHYE..NLYCVVSGEKHFLFHPP.SDRPFIPYELY.Tp20amEKV.PWIPLDPLAP
121 NKNRIAAHYDLPN..NIACSVVGRRRFTLFPP.EQLQNLYPGP-.-.....LTF.APGGQSISLV
122 NRTRIAAHQDLPD..NLACVVAGRRRFTLFPP.DQLANLYIGP-.-.....LDL.TPAGQPVSLV
123 ARSGTAIHIDPLGtsAWNSLLQGHKRWVLIPP.IAPRDLVKPMA.H.....EKG.KHPDEGITWF
124 NRTRIAAHQDLPD..NLACVVAGRRRFTLFPP.EQLANLYIGP-.-.....LDL.TPAGQPVSLV
125 NRVVASCHYDVPN..NLACCAVGQRRFTLFPP.EQIANLYPGP-.-.....LEP.TPGGQVVSMV
126 RKTPFGVHVDSCG..VFSFPVAGVKRFRLWPA.A----------.-.....---.--YGDEHPEL
127 EQANTPCHYDTFGv.NIVVQVHGCKSWLLFPP.ETPL-QSTRIP.Y.....EET.SVYCL----E
128 QDTVSPLHTDPRK..NMFVQVHGTKLFRMVAP.ESSESVYPFDG.I.....LSN.T------SQV
129 NRTVAAAHYDMSN..NIAVCAVGRRRFTLFPP.DQVANLYPGP-.-.....LEP.TPGGQVVSMV
130 EGANTPCHQDAYGy.NLVLQVQGRKRWHLFPP.EDTRKLYPTRI.P.....YEE.---SSVFSRV
131 AHLRSSTHYDPHH..NLLCVVAGCKKVTLWPP.SSSPYLYPMPV.Y.....GEAsNHSSVSIEEP
132 NRTRISAHYDVPE..NIACNVVGRRRFILFPP.EQLENLYIGP-.-.....VDF.TPAGQAISLV
133 NKTQVAAHYDFTS..NLACCLCGRRKFTLFPP.EQITNLYPGP-.-.....LEF.APGGQEISLV
134 AAAVTSLHKDHYE..NLYCVVSGEKHFLFHPP.SDRPFIPYELY.Tp38amEKV.PWIPLDPLAP
135 AGTGVPFHFHGPG..-FAEVIHGSKRWFLYPY.DERPDWNPDKT.T.....LEW.---------Y
136 LGAHTPCHLDSYGc.NLVFQVQGRKRWHLFPP.EDTPFLYPTRI.P.....YEE.---SSVFSKI
137 AGTGVPFHFHGPG..-FAEVIHGSKRWFLYPY.EQRPNWNPDKT.T.....LEW.---------Y
138 -------------..-----------------.-----------.-.....---.----------
139 SDESYKNHWDIRD..VYAIQLFGKKRWQLTAP.D---FPMPLY-.-.....---.-------MQQ
140 DCSGTALHYDVLEthAWLAVIEGKKRLALHAP.VCWDHEYEQ--.-.....---.-------QRA
141 AGLVTPLHFDAVE..VLHWMMEGRKRFVCFHP.G-LRNFYPHGI.L.....ST-.---GPFNSQV
142 TPTKTSWHRDPNP..NILSQSVGSKLVRMMPP.RSGERVFHDV-.-.....--H.SRLGTRNFNS
143 TPTYTPLHRDPNP..NLFCQLSGTKVVRLMAP.RAGDWLFRQIQa-e15emMQG.EERYKLHQAV
144 -------------..-----------------.-----------.-.....---.----------
145 HLTTTGLHTDVYAshSFSVNLCGVKCWLFIDP.KDLQTIASLYD.D.....QQL.---PSWITKD
146 TVCGLPPHYDDRD..LIIVQVAGRKHWKILGT.PV---------.-.....---.-------EGP
147 -------------..--ILQIEGEKEWLIYPE.T---LPYPTA-.-.....---.-----DQPSY
200 210 220 230
| | | |
1 WKGDPPKED.....LPDA.....EIVNLT...PG.....TMLYLPRGLWHSTKSD.QATLALN..
2 -------DP.....FEAI.....IDEELE...PG.....DILYIPPGFPHEGYAL.ENAMNYS..
3 -------DP.....FEAI.....IDEELE...PG.....DILYIPPGFPHEGYAL.ENAMNYS..
4 -------DP.....FEAI.....IDEELE...PG.....DILYIPPGFPHEGYAL.ENAMNYS..
5 -------DP.....FEAI.....IDEELE...PG.....DILYIPPGFPHEGYAL.ENAMNYS..
6 -------DP.....FEAI.....IDEELE...PG.....DILYIPPGFPHEGYAL.ENAMNYS..
7 -------EP.....FEAI.....IDEELE...PG.....DILYIPPGFPHEGYAL.ENAMNYS..
8 -------DP.....FEAI.....IDEELE...PG.....DILYIPPGFPHEGYAL.ENAMNYS..
9 -------GP.....FDAI.....IDEEME...PG.....DILYIPPGFPHEGYSL.ENALNYS..
10 -------GP.....FDAI.....IDEEME...PG.....DILYIPPGFPHEGYSL.ENALNYS..
11 -------DP.....FSAV.....IDEEME...PG.....DILYIPPGFPHEGYSI.EDSLNYS..
12 ------DRI.....GTPT.....HDFLLK...PG.....DLLYFPRGTIHQAETPsGLAHSIH..
13 HADLRILAE.....FQNG.....EDWVLE...PG.....DMLYLPPRLAHFGTAV.DECMTYS..
14 WKGDPPKED.....LPDA.....EIVNLT...PG.....TMLYLPRGLWHSTKSD.QATLALN..
15 DVDIKLLRQ.....FTPT.....HEWVLA...PG.....DMLYLPPLVPHHGVAD.DPCLTYS..
16 DVDIKLLRQ.....FTPT.....HEWVLA...PG.....DMLYLPPLVPHHGVAD.DPCLTYS..
17 DVDIKLLRQ.....FTPT.....HEWVLA...PG.....DMLYLPPLVPHHGVAD.DPCLTYS..
18 HADLRILAD.....FEQS.....DEWVLE...PG.....DMLYLPPRLAHYGIAE.DECMTYS..
19 HADLRILAE.....FEKT.....EEWTLE...PG.....DMLYLPPRLAHCGVAV.DDCLTYS..
20 HADLRILAD.....FEQS.....DEWVLE...PG.....DMLYLPPRLAHYGIAE.DECMTYS..
21 HADLRILAE.....FEKT.....EEWTLE...PG.....DMLYLPPRLAHCGVAV.DDCLTYS..
22 DVDIKLLRQ.....FTPT.....HEWVLA...PG.....DMLYLPPLVPHHGVAD.DPCLTYS..
23 ------ERI.....GRPV.....HEFMLK...PG.....DLLYFPRGTIHQADTPaGLAHSTH..
24 ------ERI.....GRPV.....HEFMLK...PG.....DLLYFPRGTIHQADTPaGLAHSTH..
25 ------ERI.....GRPV.....HEFMLK...PG.....DLLYFPRGTIHQADTPaGLAHSTH..
26 ------DRI.....GTPT.....HDFLLK...PG.....DLLYFPRGTIHQAETPsGLAYSIH..
27 ------ERI.....GRPV.....HEFMLK...PG.....DLLYFPRGTIHQADTPaGLAHSTH..
28 ------DRI.....GTPT.....HDFLLK...PG.....DLLYFPRGTIHQAETPsGLAYSIH..
29 ------DRI.....GTPT.....HDFLLK...PG.....DLLYFPRGTIHQAETPsGLAYSIH..
30 ------DRI.....GTPT.....HDFLLK...PG.....DLLYFPRGTIHQAETPsGLAHSIH..
31 HADLRILAE.....FEQS.....GEWTLE...PG.....DMLYLPPRLAHYGVAV.DDCLTYS..
32 DVELKLLRE.....FKPT.....HDWVLG...PG.....DMLYLPPLIPHHGVAE.DACLTFS..
33 HADLRILAE.....FHET.....EEWVLE...PG.....DMLYLPPRLAHCGVAV.DDCMTYS..
34 NAPMKVLTE.....FDVQ.....EDWVLN...PG.....DILYVPPGLAHWGTAV.GESITYS..
35 ------IKG.....FEPI.....IDEVME...PG.....DILYIPPGFPHDGYAI.ETSMSFS..
36 DVDIKLLRE.....FKPT.....HDWVLG...PG.....DMLYLPPLVPHHGVAQ.DACLTFS..
37 DVPLKILEH.....FEPS.....DEWVLE...PG.....DMLYLPPHIAHDGVAE.GECMTCS..
38 DVPLKILEN.....FEPS.....DEWVLE...PG.....DMLYLPPHIAHDGVAE.GECMTCS..
39 NQSIRIFDDm....GELV.....IDEVMN...PG.....DILYIPARMAHYGVAE.DDCLTFS..
40 NQSIRIFDDm....GELV.....IDEVMN...PG.....DILYIPARMAHYGVAE.DDCLTFS..
41 DAPIRVLKD.....FRME.....QEFVLE...HG.....DMLYLPPHCAHYGVAL.EPGMTYS..
42 NFTEDDMKG.....REPV.....FEGWIE...KG.....DMIYIPRGYIHQARTD.SKVHSLH..
43 GLPLKVLQN.....FHAE.....QEWLLE...PG.....DMLYLPPHIAHDGIAE.GECMTCS..
44 NQSIRIFDDm....GELV.....IDEVMN...PG.....DILYIPARMAHYGVAE.DDCLTFS..
45 NFTEDDMKG.....REPV.....FEGWIE...KG.....DMIYIPRGYIHQARTD.SKVHSLH..
46 DLPLKILAN.....FTPE.....EEFILE...PG.....DMLYLPPHYAHDGVAE.GDCMTYS..
47 DLPLKILSD.....FSAE.....QEWVLE...PG.....DMLYLPPQYAHDGVAE.GECMTAS..
48 NFSQ--FEI.....GEPI.....LDTIVN...EG.....DLLYFPRGTIHQGETI.DNTHSLH..
49 DAELKLLRE.....FEPS.....HDWVLG...PG.....DMLYLPPGVPHHGVAE.DACLTFS..
50 NFTEDDMKG.....KEPV.....FEGWIE...QG.....DMIYIPRGYTHQARTD.KKVHSLH..
51 DLPLKILSR.....FEPE.....EEHVLE...PG.....DMLYLPPQAAHDGVAEgGDCMTIS..
52 NQPIRIFDDm....GELV.....LDEVMN...PG.....DVLYVPSRMAHYGVSE.TDGLTFS..
53 NQPIRIFDDm....GELI.....LDEVMA...PG.....DILYVPSRLSHYGVAQ.DDCLTFS..
54 DLPLKILSR.....FEPE.....EEHVLE...PG.....DMLYLPPQAAHDGVAEgGDCMTIS..
55 NFSQEDL--.....GEPV.....LQTVLE...PG.....DLLYFPRGFIHQAECQ.DGVHSLH..
56 GAPLRILQN.....FNTE.....QEWVLE...PG.....DMLYLPPHVAHWGIAV.GNAMTYS..
57 ------ERI.....GRPA.....HEFMLK...PG.....DLLYFPRGTIHQADTPaGLAHSTH..
58 NFSQEDL--.....GEPV.....LQTVLE...PG.....DLLYFPRGFIHQAECQ.DGVHSLH..
59 DLPLKILAH.....FEPQ.....QEWLLE...PG.....DMLYLPPGWGHDGVAD.GECMTAS..
60 -------EP.....FEAI.....IDVIME...PG.....DILYIPPGFPHEGYAI.EPSLNFS..
61 NPNSPLVED.....FDPI.....IDMVLE...KG.....DMLYIPPGFPHCGETL.TLALSYS..
62 NFSQDDL--.....GEPV.....LQTVLE...PG.....DLLYFPRGFIHQAECQ.DGVHSLH..
63 NQPIRIFDDm....GELV.....LDEVMQ...AG.....DVLYVPSRMAHYGVSE.SESLTFS..
64 NFNEADI--.....GKPI.....LEVVLE...AG.....DLLYFPRGFIHQGDCL.PDAHSLH..
65 NYDQEQL--.....GKPI.....IDEVLS...AG.....DVLYFPRGAVHQAITE.EQQHSLH..
66 DETEFPKAM.....ELEF.....MDCILE...EG.....EMLYIPPKWWHYVRSL.TMSLSVS..
67 DETEFPKAM.....ELEF.....MDCILE...EG.....EMLYIPPKWWHYVRSL.TMSLSVS..
68 ------GRI.....GAPT.....HDFILQ...AG.....DLLYFPRGTIHQADTPaGAGHSTH..
69 NLRQDELA-.....GPPI.....VDVVLE...AG.....DLLYFPRGCIHQAATV.PGAHSLH..
70 WVISGFFND.....STKI.....DECLIGitfPG.....ECMYVPSGWWHTVINI.DDSIAIT..
71 WVISGFFND.....STKI.....DECLIGitfPG.....ECMYVPSGWWHTVINI.DDSIAIT..
72 DMPLKILAD.....FSAE.....EEWVLE...PG.....DMLYLPPQYAHDGIAE.GECMTCS..
73 CHAHLIDAL.....DEDS.....MKVVMK...PG.....CVLFVPRGYWHETTTE.EESLSLN..
74 DLEKFPKFA.....KAPF.....LSCILS...PG.....EILFIPVKYWHYVRAL.DLSFSVS..
75 DLEKFPKFA.....KAPF.....LSCILS...PG.....EILFIPVKYWHYVRAL.DLSFSVS..
76 DLEKFPKFT.....EAPF.....LSCILS...PG.....DTLFIPAKYWHYVRSL.DLSFSVS..
77 WFMNFYDDTkdw..EKKP.....IECICK...AG.....EVMFVPNGWWHLVINL.EESIAIT..
78 DFDSFPSMR.....QAQL.....IECTLA...PG.....ELLFLPVGWWHYVEGI.DASVTMT..
79 KSSSFTPPE.....KEAY.....LSCILH...PG.....DVLYIPRGHWHYAVTK.EE-PSIH..
80 LEIYPSLAL.....SARP.....LECTIQ...AG.....EVLYFPDRWWHATLNL.DTS----..
81 LEIYPSLAL.....SARP.....LECTIQ...AG.....EVLYFPDRWWHATLNL.DTS----..
82 NLSDYPRAEhs...LKQS.....QEITLN...AG.....DAVFIPEGWFHQVDSD.ELTVAVN..
83 RDTYPALPP.....SARP.....LECTIR...AG.....EVLYFPDRWWHATLNL.DTS----..
84 RDTYPALPP.....SARP.....LECTIR...AG.....EVLYFPDRWWHATLNL.DTS----..
85 DFDNPDYER.....FPNFqnvvgYETVVG...PG.....DVLYIPMYWWHHIESLlNGGITIT..
86 QSRKGVGAD.....GPASw....TDVCLR...PG.....DVLYLPRGQVHSARTH.SE-PSVH..
87 DFDNPDYER.....FPNFrnvvgYETVVG...PG.....DVLYIPMYWWHHIESLlNGGITIT..
88 NVIYPRTQLpt...WPP-efkp.LEILQK...PG.....ETVFVPGGWWHVVLNL.DTTIAIT..
89 NVIYPRTQLpt...WPP-efkp.LEILQK...PG.....ETVFVPGGWWHVVLNL.DTTIAIT..
90 DFENPDFER.....FPNFrnvlgYETVVG...PG.....DVLYIPMYWWHHIESLmDGGITIT..
91 NVIYPRTQLpt...WPP-efkp.LEILQK...PG.....ETVFVPGGWWHVVLNL.DTTIAIT..
92 NVIYPRTQLpt...WPP-efkp.LEILQK...PG.....ETVFVPGGWWHVVLNL.DTTIAIT..
93 NVVYPRTQLps...WPPEfkp..LEILQK...PG.....ETVFVPGGWWHVVLNF.DTAIAVT..
94 NVIYPRTQLpt...WPP-efkp.LEILQK...PG.....ETVFVPGGWWHVVLNL.DTTIAIT..
95 DLDHPDLDR.....YPAFrdvkvLEVVLE...PG.....DTVFLPLGWWHQVASL.EVSLSFS..
96 DYNRFPLVR.....DVRF.....YRLTLR...RG.....EVLYIPPKWWHYVESL.SPSFSVS..
97 NVNEFPRTG.....DVEF.....MDGILE...EG.....DLLYIPPKWWHYVRSL.STSFSVS..
98 DFDNPDYER.....FPNFqnvvgYETVVG...PG.....DVLYIPMYWWHHIESLlNGGITIT..
99 DFDNPDYER.....FPNFqnvvgYETVVG...PG.....DVLYIPMYWWHHIESLlNGGITIT..
100 DFDNPDYER.....FPNFqnvvgYETVVG...PG.....DVLYIPMYWWHHIESLlNGGITIT..
101 DFENPDFER.....FPNFrnvlgYETVVG...PG.....DVLYIPMYWWHHIESLmDGGVTIT..
102 DMENTYPCP.....SEPY.....DDFVLE...TG.....DVLYLPRGWWHNPLPL.GE-ETIH..
103 ASYGPFTAV.....EDKV.....YHVMLE...PG.....MALIVPPKWWHYVETL.EPALNFN..
104 DFDNPDYEK.....FPNFknvvgYEAVVG...PG.....DVLYIPMYWWHHIESLlNGGVTIT..
105 DFDNPDYER.....FPNFqnvvgYETVVG...PG.....DVLYIPXYWWHHIESLlNGGITIT..
106 QTVYKRVRS.....PSWPkeyapIECRQG...PG.....ETMFVPSGWWHVVINE.EYTIAVT..
107 DFENPDYDK.....FPNFknavgYEAVVG...PG.....DVLYIPMYWWHHIESLlNGGETIT..
108 VKVYPKVKS.....PTWPkeyapLEIIQH...PG.....ETVFVPGGWWHVVLNL.DQTVAVT..
109 DIADPGEAP.....TEPV.....ADLVLW...PG.....DVLYVPRGVWHAVSAD.QGVRSLH..
110 DVAHPDLQR.....FPRFad7haRSVVLE...PG.....DALFIPSMWWHHVQSL.HP-----..
111 DIDHSHQPP.....EGTV.....WEGTVR...AG.....EVLHVPRGWWHTVTGT.GD-VSMH..
112 TKDTDISIP.....EHID.....MDIILE...AG.....DVLYIPRGWWHRPIPL.GC-ETFH..
113 NVVNPDLKR.....FPQFrkaqrHAVTLS...PG.....QVLFVPRHWWHYVESI.DP-----..
114 NVVNPDLKR.....FPQFrkaqrHAVTLS...PG.....QVLFVPRHWWHYVESI.DP-----..
115 NVVNPDLKR.....FPQFqkarrHMVTLS...PG.....QVLFVPRHWWHYVESL.DP-----..
116 NVVNPDLKC.....FPQFqkarrHMVTLS...PG.....QVLFVPRHWWHYVESL.DP-----..
117 NPDAPDYER.....FPKArdvtfMRVTLE...AG.....DLLFLPEGWFHQVESV.STSLSVN..
118 DFDAPDLQR.....FPRFae7haVSAELG...PG.....DALLIPSMWWHRMQAL.DA-----..
119 QLGPDPVGG.....RPPA.....IDTVLE...PG.....DALYLPRGWLHSARTT.ED-RSIH..
120 DLARYPSYS.....QAQA.....LRCTVR...AG.....EMLYLPALWFHHVQQS.QGCIAVN..
121 DFYAPDFDK.....FPRFrn7saQVAELE...PG.....DAVFIPSMWWHHVESL.DK-----..
122 DIAAPDLQR.....FPRYaq7haLVAELA...PG.....DALFIPSMWWHHVEAL.ES-----..
123 QTVYKRVRS.....PSWPkeyapIECRQG...PG.....ETMFVPSGWWHVVINE.EYTIAVT..
124 DITAPDLER.....FPRYaq7haLVADLE...PG.....DAVFMPSMWWHHIQAL.DG-----..
125 DLAAPDLQR.....YPRFaq7haRTAVLQ...PG.....NAVFIPSMWWHHVMAL.QP-----..
126 DRTFNYEKH.....KKHS.....QLVEVG...PG.....DMTYWPSSEWHIAESDgSFSATWS..
127 NFYAPDPAKis7hlGRQA.....YHCNLQ...PG.....NVLIVPRHWWHYVEAK.STSLSVN..
128 DVENPDLKI.....FPNFeqvevLDAVIN...PG.....DAIFIPEKWWHFVRST.SPSISIS..
129 DFETPDFDR.....HPRFre7saQVAEME...PG.....DVLVYPALWWHQVEAL.DG-----..
130 DVLQPDLRR.....FPAFrgaraHVVTLQ...PGq15csEVLYVPRHWWHYVESV.DP-----..
131 DYSRYTRARym...KEYS.....ERVILN...CG.....DALFIPEGWYHQVDSD.DLTIAIN..
132 DFHNPDPIK.....FPNFik7saLVVDLE...PG.....DALYIPSMWWHHVEGL.DA-----..
133 DFQQPDFRR.....FPRFkn7faQTVILS...PG.....DALFLPSMWWHHVEGL.DA-----..
134 DLARYPSYS.....QAQA.....LRCMVR...AG.....EMLYLPALWFHHVQQS.QGCIAVN..
135 TYDYPKLPR.....DKLP.....LECEMK...PG.....ELIYFPDKWWHATLNI.K------..
136 NVVNPDLKR.....FPQFrkaqrHAVTLS...PG.....QVL-------------.-------..
137 TYDYPKLSR.....DELP.....LECEMK...SG.....EVIYFPDKWWHATLNI.ESS----..
138 ---------.....----.....------...--.....----------------.-------..
139 TKDTDISIP.....EHID.....MDIILE...AG.....DVLYIPRGWWHRPIPL.GC-ETFH..
140 QALQVLETR.....CNQG.....EWCYLEvn.KG.....DLLYIPATWWHEVVNE.GPTISLT..
141 NADAPDLRA.....FPRFrrtqpIEFVLQ...AG.....EVLYIPAYYWHQVESL.DA-----..
142 RFRGMELLD.....GPEAt18emVEATLN...PD.....ESLFIPKGWWHSVKSL.NPGTAFNgl
143 WEAGPDSPV.....PPGT.....YEVVLN...PG.....DAMFIPTHYWHSVKSV.GES----..
144 ---------.....----.....------...--.....----------------.-------..
145 DLFRGPLVN.....HRHL.....IKILFQy..PG.....QTVFVPSGWYHQVLNI.GTTLSIN..
146 WRKRTMSVP.....DTVT.....DEFVMQ...GG.....DMLFVPAGLYHQCVPL.EP--SLH..
147 ---DRLPPE.....EPPY.....LQQVLS...PG.....DLLYIPRGHWHYAIAQ.ET-ASLH..
240 250 260
| | |
1 ITFGQ.....P.....A....WLDL.MLAALR...KKL...IS.....DN.....RFR..ELAV.
2 VGFRA.....P.....N....TREL.ISGFAD...YVL...QRelg..GN.....YYS..DPDV.
3 VGFRA.....P.....N....TREL.ISGFAD...YVL...QRelg..GN.....YYS..DPDV.
4 VGFRA.....P.....N....TREL.ISGFAD...YVL...QRelg..GN.....YYS..DPDV.
5 VGFRA.....P.....N....TREL.ISGFAD...YVL...QRelg..GN.....YYS..DPDV.
6 VGFRA.....P.....N....TREL.ISGFAD...YVL...QRelg..GN.....YYS..DPDV.
7 VGFRA.....P.....N....SREL.ISGFAD...YVL...QRelg..NT.....YYS..DPDM.
8 VGFRA.....P.....N....SREL.ISGFAD...YVL...QRdlg..NT.....YYS..DPDM.
9 VGFRA.....P.....S....GREL.VSGFAD...YVL...ARelg..SY.....RYS..DPDL.
10 VGFRA.....P.....S....GREL.VSGFAD...YVL...ARelg..SY.....RYS..DPDL.
11 VGFRA.....P.....N....SREL.FSSFAD...YVL...ANdlg..SY.....RYS..DADL.
12 LTISTyqn..N.....S....WGDY.LLDSIS...GLV...FDiak..ED.....VAL..RTGM.
13 VGFRA.....P.....S....AAEV.LTHFTDflaQFL...PD.....EE.....RYG..DPGI.
14 ITFGQ.....P.....A....WLDL.MLAALR...KKL...IS.....DN.....RFR..ELAV.
15 LGMRA.....P.....S....SAEL.ISDWLD...TLI...SE.....ADeav..RYQ..DADL.
16 LGMRA.....P.....S....SAEL.ISDWLD...TLI...SE.....ADeav..RYQ..DADL.
17 LGMRA.....P.....S....SAEL.ISDWLD...TLI...SE.....ADeav..RYQ..DADL.
18 IGFRA.....P.....S....AAEV.LTHFTDflgQFL...SD.....EE.....RYT..DAGL.
19 VGFRA.....P.....S....AAEV.LTHFTDflsQFI...PD.....EE.....RYT..DADA.
20 IGFRA.....P.....S....AAEV.LTHFTDflgQFL...SD.....EE.....RYT..DAGL.
21 VGFRA.....P.....G....AAEV.LTHFTDflsQFI...PD.....EE.....RYT..DADA.
22 LGMRA.....P.....S....SAEL.MSDWLD...TFI...SE.....ADeav..RYQ..DAGL.
23 VTISTyqn..N.....S....WGDF.LLDTIS...GLV...FDtak..ED.....VEL..RTGI.
24 VTISTyqn..N.....S....WGDF.LLDTIS...GLV...FDtak..ED.....VEL..RTGI.
25 VTISTyqn..N.....S....WGDF.LLDTIS...GLV...FDtak..ED.....VEL..RTGI.
26 LTISTyqn..N.....S....WGDC.LLDSIS...GFV...FDiak..ED.....VAL..RSGM.
27 VTISTyqn..N.....S....WGDF.LLDTIS...GLV...FDtak..ED.....VEL..RTGI.
28 LTISTyqn..N.....S....WGDC.LLDSIS...GFV...FDiak..ED.....VAL..RSGM.
29 LTISTyqn..N.....S....WGDC.LLDSIS...GFV...FDiak..ED.....VAL..RSGM.
30 LTISTyqn..N.....S....GGDY.LLDSIS...GLV...FDiak..ED.....VAL..RTGM.
31 VGFRA.....P.....S....AAEV.LTHFTDflgQFL...PD.....EE.....RYS..DADA.
32 IGTRA.....P.....S....SAEL.IGDYLD...TLI...AD.....ADeav..RYH..DEDL.
33 VGFRA.....P.....S....AAEV.LTHFTDflsQFL...TD.....EE.....RYT..DADA.
34 VGFRA.....P.....S....HQDI.VLDFSQ...EVA...SKiee..DN.....RYQ..DQFL.
35 VGFRS.....P.....K....KQEL.LSSFAD...FII...SNdig..DV.....HYH..NPSI.
36 IGTRA.....P.....S....SAEL.IGDYLD...TLI...AD.....ADeav..RYH..DEDL.
37 IGFRA.....P.....S....AGEL.GAQFLY...YLA...ERsg8rgDE.....LYR..DPKQ.
38 IGFRA.....P.....S....AGEL.GAQFLY...YLA...ERgg8gdDD.....LYR..DPKQ.
39 FGLRY.....P.....N....LSNL.IDGISK...GFC...HQ.....DPdl...NLS..EFDL.
40 FGLRY.....P.....N....LSNL.IDGISK...GFC...HQ.....DPdl...NLS..EFDL.
41 IGFRA.....P.....P....AQEL.AAQFLV...YLQ...DRvci..DG.....VYA..DPDL.
42 VTVSTgrq..W.....S....FANL.MEKVVPeaiGVL...TD.....TR.....HKL..RRGL.
43 IGFRA.....P.....S....ASEL.TAQFLY...HLA...ERge7haGA.....LYR..DPQQ.
44 FGLRY.....P.....N....LSNL.IDGISK...GFC...HQ.....DPdl...NLS..EFDL.
45 VTVSTgrq..W.....S....FANL.MEKVVPeaiGVL...TD.....TR.....HKL..RRGL.
46 VGFRS.....P.....S....YREL.AGHFLG...FLS...QTle7dfEG.....RYT..DPEQ.
47 IGFRA.....P.....A....YREL.AGHFLA...WLS...ETva7glDG.....RYA..DAGE.
48 ITLSVyqk..N.....S....WGDF.LEKLLPnalTAA...IK.....EN.....YEF..RKGL.
49 VGMRA.....P.....S....AAEL.MGDYID...---...--.....--.....---..----.
50 VTVSTgrq..W.....S....FANL.MEKVIPeavGAL...TE.....ER.....HKL..RRGL.
51 IGFRA.....P.....SqamlARGL.LEAAAD...QVM...ARv18rlDG.....LYR..DPGQ.
52 FGLRY.....P.....N....AADL.LENFCK...TLE...HH.....SEvi...AGS..EFNI.
53 FGLRY.....P.....N....VADL.FDNINK...GMC...QAlp...EI.....DLT..ELNI.
54 IGFRA.....P.....SqamlARGL.LEAAAD...QVM...ARv18rlDG.....LYR..DPGQ.
55 LTLSTyqr..N.....T....WGDF.LEAVLPlamQAA...IE.....EN.....VEF..RRGL.
56 IGFRA.....P.....S....VQEL.VSEFLN...DLQ...DRlqi..PG.....MYA..DPDL.
57 VTIST.....-.....-....----.------...---...--.....--.....---..----.
58 LTLSTyqr..N.....T....WGDF.LEAVLPlavQAA...IE.....EN.....EEF..RRGL.
59 IGFRA.....P.....A....RGEL.AREVLA...RLL...ER.....EDdaprvLYR..DAAQ.
60 VGFRA.....P.....D....AKAL.ISSFAD...HLIdneVR.....TE.....RYG..DADL.
61 IGYRA.....P.....S....QQEL.VSEVAD...YLL...DKnlg..QQ.....RFT..SASE.
62 LTLSTyqr..N.....T....WGDF.LEAILPlavQAA...ME.....EN.....VEF..RRGL.
63 FGLRY.....P.....N....ATDI.LEKLAN...TLT...YQ.....HE.....IMPnvDFNI.
64 ITISSyqk..N.....S....WGDL.LQRMLP...AALeiaVE.....ED.....TEF..RRGL.
65 ITLSVyqq..Q.....A....YANL.LETLMPmvlKKA...VD.....RS.....VAL..RRGL.
66 FWW--.....-.....-....----.------...---...--.....--.....---..----.
67 FWW--.....-.....-....----.------...---...--.....--.....---..----.
68 LTLSTyq...-n35crS....WGDL.LLDLMP...GCV...FDrmk..TD.....CEL..RTGL.
69 ITVSVyqr..N.....C....WADL.FEQMLP...IALataAD.....TE.....PQL..REGL.
70 QNFVP.....K.....S....KLAE.VLNFLKnk.PKQ...IS.....GF.....RLK..EIKQ.
71 QNFVP.....K.....S....KLAE.VLNFLKnk.PKQ...IS.....GF.....RLK..EIKQ.
72 IGFRA.....P.....A....YREL.AGHFLA...WLS...ETve7dlGG.....RYA..DPGE.
73 FTFSQ.....P.....T....WADV.FTKSLQ...EVL...LR.....SP.....EWR..ELAD.
74 FWW--.....-.....-....----.------...---...--.....--.....---..----.
75 FWW--.....-.....-....----.------...---...--.....--.....---..----.
76 FWW--.....-.....-....----.------...---...--.....--.....---..----.
77 QNYAS.....R.....S....NLLN.VLEFLK...KPN...A-.....--.....---..----.
78 FT---.....-.....-....----.------...---...--.....--.....---..----.
79 LTLGIhs...S.....T....GVDL.LEWLIG...QLQ...YR.....EE.....WRT..SLAL.
80 -----.....-.....-....----.------...---...--.....--.....---..----.
81 -----.....-.....-....----.------...---...--.....--.....---..----.
82 FWWQS.....N.....Y....MSNM.PEHMDS...YYL...--.....--.....---..-RRI.
83 -----.....-.....-....----.------...---...--.....--.....---..----.
84 -----.....-.....-....----.------...---...--.....--.....---..----.
85 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IM.....RN.....IEK..MLGE.
86 LTVGLha...P.....T....VLTL.VTSALH...ALS...LR.....DP.....RVH..DRLP.
87 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IM.....RN.....IEK..MLGE.
88 QNFAS.....-.....-....----.------...---...--.....--.....---..----.
89 QNFAS.....-.....-....----.------...---...--.....--.....---..----.
90 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IM.....RN.....IEK..MLGE.
91 QNFAS.....-.....-....----.------...---...--.....--.....---..----.
92 QNFAS.....-.....-....----.------...---...--.....--.....---..----.
93 QNFAS.....-.....-....----.------...---...--.....--.....---..----.
94 QNFAS.....-.....-....----.------...---...--.....--.....---..----.
95 F----.....-.....-....----.------...---...--.....--.....---..----.
96 FW---.....-.....-....----.------...---...--.....--.....---..----.
97 FWWR-.....-.....-....----.------...---...--.....--.....---..----.
98 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IM.....RN.....IEK..MLGE.
99 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IM.....RN.....IEK..MLGE.
100 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IM.....RN.....IEK..MLGE.
101 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IM.....RN.....IEK..MLGE.
102 LSVGIf....P.....P....YAHE.YINWLS...YKI...--.....--.....--T..DIDI.
103 TWLGLvre..T.....-....----.------...---...--.....--.....---..----.
104 VNFWYkgaptP.....K....RIEY.PLRAHQ...KVA...IT.....RN.....IEK..MLGE.
105 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IX.....RN.....IEK..XLGE.
106 HNYCS.....-.....-....----.------...---...--.....--.....---..----.
107 VNFWYkgaptP.....K....RIEY.PLKAHQ...KVA...IM.....RN.....IEK..MLGE.
108 QNFSS.....P.....T....NFHV.VW----...---...--.....--.....---..----.
109 VTCGLqt...H.....T....ATDL.MAWVSE...QLL...TH.....ED.....WRR..DLPLl
110 FNVLI.....N.....Y....WWSR.APAHLP...AAM...--.....-P.....ALY..HALW.
111 LTFGFtratgV.....D....WARW.LVDRLY...EVE...--.....--.....-FA..RRDL.
112 FAVGTfp...P.....N....GYNY.LEWLMK...KFP...--.....--.....---..----.
113 VTVSI.....N.....S....WIEL.EEDHLA...RV-...--.....--.....---..----.
114 VTVSI.....N.....S....WIEL.EEDHLA...RV-...--.....--.....---..----.
115 VTVSI.....N.....S....WIEL.EEDHLA...RV-...--.....--.....---..----.
116 VTVGI.....N.....S....WIEL.EEDHLA...RV-...--.....--.....---..----.
117 FWV--.....-.....-....----.------...---...--.....--.....---..----.
118 FNVLV.....N.....Y....WWRQ.SPRWMD...TPM...--.....-N.....ALL..HAIM.
119 LTVGLla...T.....T....WADV.LTDAVAsa.GVA...--.....-D.....VAL..RRAL.
120 FWY--.....-.....-....----.------...---...--.....--.....---..----.
121 LNVLI.....N.....Y....WWRE.TPAFMG...PPI...--.....-N.....VLH..HALL.
122 FNVLV.....N.....F....WWRQ.GPAYMD...SPM...--.....-N.....ALM..LALL.
123 HNYCS.....-.....-....----.------...---...--.....--.....---..----.
124 FNVLV.....N.....F....WWRQ.SPAYMD...SPM...--.....-N.....ALM..LALL.
125 FNVLV.....N.....Y....WWGS.MPAHVP...APM...--.....-P.....ALY..HALW.
126 LGVWVd....Q.....T....HGDM.FGSALK...DLV...--.....--.....---..----.
127 YWVPL.....K.....V....DMDL.ILD---...---...--.....--.....---..----.
128 FWF--.....-.....-....----.------...---...--.....--.....---..----.
129 FNVLM.....N.....Y....WWNA.TPAFVD...TPM...--.....-T.....TLL..HGLL.
130 VTVSV.....N.....S....WIEL.VRFLLP...RFL...LP.....RF.....LLP..RFL-.
131 FWWKS.....R.....I....MNEM.LEHMDA...YYL...R-.....--.....---..----.
132 CNVLV.....N.....Y....WWND.IDVHVP...---...-P.....SD.....ALL..HGLM.
133 VNVLY.....T.....H....WWRE.SPAYYG...RPS...--.....-N.....ALL..HTLL.
134 FWY--.....-.....-....----.------...---...--.....--.....---..----.
135 -----.....-.....-....----.------...---...--.....--.....---..----.
136 -----.....-.....-....----.------...---...--.....--.....---..----.
137 -----.....-.....-....----.------...---...--.....--.....---..----.
138 -----.....-.....-....----.------...---...--.....--.....---..----.
139 LAVGTfp...P.....N....GYNY.LEWLMK...KFP...--.....--.....---..----.
140 RNFVS.....P.....E....IART.VTSC--...---...--.....--.....---..----.
141 -----.....-.....-....----.------...---...--.....--.....---..----.
142 LNVSV.....N.....Y....W---.------...---...--.....--.....---..----.
143 -----.....-.....-....----.------...---...--.....--.....---..----.
144 -----.....-.....-....----.------...---...--.....--.....---..----.
145 HNWCNa....S.....C....ILQM.YTALKE...QYE...VS.....AE.....SL-..----.
146 LGALItr...P.....C....GADL.LKMVQP...---...--.....--.....---..----.
147 LTIGI.....H.....T....ATGLdWVNWLQ...QQ-...LR.....DQ.....PHW..RQGL.
270 280 290 300 310
| | | | |
1 N.....HQ.....SLHESSKSELNGYLESLIQTLS...EN...AETLTP.EQIFQSQDSDFDPYQ
2 P.....PR.....AHPADVLPQEMDKLREMMLELInqpEH...FKQWFG.EFISQSRHELDIAPP
3 P.....PR.....AHPADVLPQEMDKLREMMLELInqpEH...FKQWFG.EFISQSRHELDIAPP
4 P.....PR.....AHPADVLPQEMDKLREMMLELInqpEH...FKQWFG.EFISQSRHELDIAPP
5 P.....PR.....AHPADVLPQEMDKLREMMLELInqpEH...FKQWFG.EFISQSRHELDIAPP
6 P.....PR.....AHPADVLPQEMDKLREMMLELInqpEH...FKQWFG.EFISQSRHELDIAPP
7 P.....SR.....KHPADILPQEMDKLRNMMLDLInqpAH...FQQWLG.EFLSQSRHELDIAPP
8 P.....SR.....KHPADILPQEMDKLRNMMLDLInqpAH...FQQWLG.EFISQSRHELDIAPP
9 Q.....LR.....EHPAEVLPSEVDKLRTMMLDLVqqpEH...FQNWFG.EFISQSRHELDIAPP
10 Q.....LR.....EHPAEVLPSEVDKLRTMMLDLVqqpEH...FQNWFG.EFISQSRHELDIAPP
11 T.....FR.....ENPALVQPHELSALHTMMNELLaqpDT...FQQWFG.EFISQSRHELDIAPP
12 P.....RRm....LMNVETPADVTRKLSGFLRTLA...DQ...LEG-RK.ELLSSDMKKDFVMHR
13 G.....PC.....EDPHQIQRDALERLKGLIQEHM...GD...------.---------------
14 N.....HQ.....SLHESSKSELNGYLESLIQTLS...EN...AETLTP.EQIFQSQDSDFDPYQ
15 T.....RP.....EDPYEIDAAATDRAIAALNALR...MH...------.-----------EDPE
16 T.....RP.....EDPYEIDAAAMDRAIAALNALR...MH...------.-----------EDPE
17 T.....RP.....EDPYEIDAAAMDRAIAALNALR...MH...------.-----------EDPE
18 Q.....PVg....DDPHQIQRDALERLQGLIQEHM...SD...------.---------------
19 Q.....PV.....SDPHQIQHDALDRLKTLLAEHM...SD...------.---------------
20 Q.....PVg....DDPHQIQRDALERLQGLIQEHM...SD...------.---------------
21 Q.....PV.....SDPHQIQHDALDRLKALLAEHM...SD...------.---------------
22 T.....RP.....DDPYEIDAAAMDRAIAALDALR...MH...------.-----------DDPE
23 P.....RQ.....LLLVESTTVATRRLSGFLRTLA...DR...LEG-TK.ELLSSDMKKDFIMHR
24 P.....RQl....LLQVESTTVATRRLSGFLRTLA...DR...LEG-TK.ELLSSDMKKDFIMHR
25 P.....RQ.....LLLVESTTVATRRLSGFLRTLA...DR...LEG-TK.ELLSSDMKKDFIMHR
26 P.....RRm....LLNVETPADVTRKLSGFLRTLA...DQ...LEG-RE.ELLSSDMKKDFVKHR
27 P.....RQl....LLQVESTTVATRRLSGFLRTLA...DR...LEG-TK.ELLSSDMKKDFIMHR
28 P.....RRm....LLNVETPADVTRKLSGFLRTLA...DQ...LEG-RE.ELLSSDMKKDFVKHR
29 P.....RRm....LLNVETPADVTRKLSGFLRTLA...DQ...LEG-RE.ELLSSDMKKDFVKHR
30 P.....RRm....LMNVETPADITRKLSVFLRTLA...DQ...LEG-RK.ELLSSDMKKDFVMHR
31 Q.....PV.....SDPHQIQHDALDRLKALLDKHM...GD...K-----.D--------------
32 K.....VP.....ADPYEIDVTAMNRVVAALNALR...MN...DPDRLG.DWFG-----------
33 K.....PVs....DDPHQIQHDALGRLKALLAEHM...SD...------.---------------
34 T.....AN.....KNAGEITGDAIEQLKHILQTYM...QDeqaLAQWLG.KSMTQLNPGMVD---
35 P.....AR.....QNSGAILAAECNDLEAMMRSLL...DHpdlMKQWMG.EHLSHSRHELDIISS
36 K.....VP.....ADPYEIDVTAMNRVVAALNALR...MN...DPDRLG.DWFG-----------
37 P.....AV.....DTPAELPPAMVERVAEIVDAIR...WR...K-----.---------------
38 P.....AV.....DTPAQLPPAMVERVAEIVDAIR...WR...K-----.---------------
39 P.....LR.....LSQSEQR---------------...--...------.---------------
40 P.....LR.....LSQSEQR---------------...--...------.---------------
41 K.....LQ.....ADPAKIGGEMIDQVAGLLSKIR...WD...KDT---.---------------
42 Ptg8ggVI.....DLDYSQEDHFVEKFKMVVDRHM...SM...LRNLVA.DQLLE----------
43 P.....AV.....ERPAELPAALVERVGAILAGIK...WKeqdIASFLG.TYLS-----------
44 P.....LR.....L---------------------...--...------.---------------
45 Ptg8ggVI.....DLDYSQEDHFVEKFKMVVDRHM...SM...LRNLVA.DQLLE----------
46 K.....PV.....ERPGELPTAMVRALAQKLNALR...WT...------.---------------
47 S.....AT.....STPAQLPANLARAVAERLQSLK...WN...A-----.---------------
48 P.....ID.....YLRY------CGYVHSEIQNNS...KD...KFKEKI.KHLLSKLIDYIDIDE
49 -.....--.....----------------------...--...------.---------------
50 P.....IGlf8vvDLDYSQEEHFTEKFKIVVDRHM...SR...LRNLVA.DHLLDS---------
51 P.....AV.....AHPAAVPDGLVEATLATLDRLR...--...------.---------------
52 P.....FR.....LAPHEQPNALLDP---------...--...------.---------------
53 P.....LR.....LSPATQ----------------...--...------.---------------
54 P.....AV.....AHPAAVPDGLVEATLATLDRLR...--...------.---------------
55 P.....RD.....FMDY------------------...--...------.---------------
56 Q.....LQ.....RHPAEIGTQMLNKVGAMLDQIR...WQ...SED---.---------------
57 -.....--.....----------------------...--...------.---------------
58 P.....RD.....FMDY------------------...--...------.---------------
59 P.....AT.....DAPGRIPEELQRFAVDAV----...--...------.---------------
60 K.....PR.....ARHGEIQPHELHRLRELMQQAL...DDetlFKEWFG.TMISEAKHDLDVNPV
61 Ptn...PG.....IISQDHQLGIMSLLSQLAQDPA...SY...-QVVLG.KLLSQNRFELDICEG
62 P.....RD.....FMDY------------------...--...------.---------------
63 P.....FR.....LSP-------------------...--...------.---------------
64 P.....LD.....YLT-------------------...--...------.---------------
65 P.....LH.....TFQV-LGNAYKGNDCGSRKQLV...EN...VQKLVT.NYLMPSEDDIDEAVD
66 -.....--.....----------------------...--...------.---------------
67 -.....--.....----------------------...--...------.---------------
68 P.....RGl....LTTPSISPAVSHQLSVFLRRLA...DV...VDQQGQ.SLRSSSMRRDFISHR
69 P.....LD.....LHQH------------------...--...------.---------------
70 C.....LD.....FIAKDSSDEVLTRYLEAFNSLT...ID...LEEDCG.EL-------------
71 C.....LD.....FIAKDSSDEVLTRYLEAFNSLT...ID...LEEDCG.EL-------------
72 R.....AA.....KHPAQLPAGMAKAVAQRLKALQ...WN...------.---------------
73 G.....LE.....GTDQERKEAAIARFEFLLKSLA...TE...LPEISG.RLLL-----------
74 -.....--.....----------------------...--...------.---------------
75 -.....--.....----------------------...--...------.---------------
76 -.....--.....----------------------...--...------.---------------
77 -.....--.....----------------------...--...------.---------------
78 -.....--.....----------------------...--...------.---------------
79 R.....ID.....DTSFNVS------VENLIKDLK...EY...INNHNIsEEYNNYLDGLAKPFE
80 -.....--.....----------------------...--...------.---------------
81 -.....--.....----------------------...--...------.---------------
82 T.....RR.....LIDREMSLLVSKPSSTDLRHLS...EH...IDQSRI.EMAEGGNDNIG----
83 -.....--.....----------------------...--...------.---------------
84 -.....--.....----------------------...--...------.---------------
85 A.....L-.....GNPQEVGPLLNTMI--------...--...------.---------------
86 P.....RH.....LDDAQVRAGLGEAVRDAVRALD...DD...------.---------------
87 A.....L-.....GNPQEVGPLLNTMI--------...--...------.---------------
88 -.....--.....----------------------...--...------.---------------
89 -.....--.....----------------------...--...------.---------------
90 A.....L-.....GNPQEVGPLLNTMVK-------...--...------.---------------
91 -.....--.....----------------------...--...------.---------------
92 -.....--.....----------------------...--...------.---------------
93 -.....--.....----------------------...--...------.---------------
94 -.....--.....----------------------...--...------.---------------
95 -.....--.....----------------------...--...------.---------------
96 -.....--.....----------------------...--...------.---------------
97 -.....--.....----------------------...--...------.---------------
98 A.....L-.....GNPQEVGPLLNTMI--------...--...------.---------------
99 A.....L-.....GNPQEVGPLLNTMI--------...--...------.---------------
100 A.....L-.....GNPQEVGPLLNTMI--------...--...------.---------------
101 A.....L-.....GNPQEVGPLLNTM---------...--...------.---------------
102 G.....RK.....SLPRSWKQA-------------...--...------.---------------
103 -.....--.....----------------------...--...------.---------------
104 A.....LG.....D---------------------...--...------.---------------
105 A.....L-.....GNPQEVGPLLNTX---------...--...------.---------------
106 -.....--.....----------------------...--...------.---------------
107 A.....L-.....GDPHEVGPLL------------...--...------.---------------
108 -.....--.....----------------------...--...------.---------------
109 A.....AP.....DVQADAVDGMRKRLAELLDD--...--...------.---------------
110 A.....IR.....DRPTAEKQAWRALFDYYVFGPA...EQ...AGEHLP.EPARHALGPID----
111 P.....RF.....ATPEERR----KHQHELLRHLM...DL...AEQHGL.DEFLTDRDSRFPRRQ
112 -.....--.....----------------------...--...------.---------------
113 -.....--.....----------------------...--...------.---------------
114 -.....--.....----------------------...--...------.---------------
115 -.....--.....----------------------...--...------.---------------
116 -.....--.....----------------------...--...------.---------------
117 -.....--.....----------------------...--...------.---------------
118 S.....VR.....DLPPAQREIWREAFRHYVFDAD...AQ...TAAHIP.EAVRGVLGPMDE---
119 P.....LP.....GAPGAA----------------...--...------.---------------
120 -.....--.....----------------------...--...------.---------------
121 T.....LR.....DLPPEQRQAWKNIFNHYIFDAD...ES...TNAHIP.EQALGFLGELDD---
122 T.....IR.....DLPAEQRATWQEVFRHYVFEPD...DS...TAAHLP.DAARGVLAPMD----
123 -.....--.....----------------------...--...------.---------------
124 T.....IR.....DLPAEQRATWQEVFRHYVFDAD...AD...TAAHLP.EAARGVLAPMDD---
125 S.....IR.....DRPAAEKAAWRAVFDYYVFGPA...EQ...AGAHLP.EAARQVLGTID----
126 -.....--.....----------------------...--...------.---------------
127 -.....--.....----------------------...--...------.---------------
128 -.....--.....----------------------...--...------.---------------
129 S.....LR.....DRPDFEKQGWKALFDYYVFGPA...ER...AGAHLP.DDARGPLGALDD---
130 -.....--.....----------------------...--...------.---------------
131 -.....--.....----------------------...--...------.---------------
132 A.....IR.....QLPEEKRIIWKRLFDYYLFSS-...--...------.---------------
133 G.....LS.....GLSSNQRKAWRSIFDYYVF---...--...------.---------------
134 -.....--.....----------------------...--...------.---------------
135 -.....--.....----------------------...--...------.---------------
136 -.....--.....----------------------...--...------.---------------
137 -.....--.....----------------------...--...------.---------------
138 -.....--.....----------------------...--...------.---------------
139 -.....--.....----------------------...--...------.---------------
140 -.....--.....----------------------...--...------.---------------
141 -.....--.....----------------------...--...------.---------------
142 -.....--.....----------------------...--...------.---------------
143 -.....--.....----------------------...--...------.---------------
144 -.....--.....----------------------...--...------.---------------
145 -.....--.....----------------------...--...------.---------------
146 -.....--.....----------------------...--...------.---------------
147 P.....LA.....GSCNFDPLKLRGHLESLRDQLI...TY...LQ----.---------------
320 330
| |
1 STQLVFRQLLTSYKF
2 EPPYQPDEIYDALK-
3 EPPYQPDEIYDALK-
4 EPPYQPDEIYDALK-
5 EPPYQPDEIYDALK-
6 EPPYQPDEIYDALK-
7 EPPYQPDEIYDALK-
8 EPPYQPDEIYDALK-
9 EPPYQTGDIYELLK-
10 EPPYQTGDIYELLK-
11 EPPYESDEIYELMK-
12 LPPFCVGNGTESM--
13 ---------------
14 STQLVFRQLLTSYKF
15 QLGNWFGRFITTY--
16 QLGNWFGRFITTY--
17 QLGNWFGRFITTY--
18 ---------------
19 ---------------
20 ---------------
21 ---------------
22 QLGNWFGRFITTY--
23 LPPYSAGDG------
24 LPPYSAGDG------
25 LPPYSAGDG------
26 LPPFFEGNGTET---
27 LPPYSAGDG------
28 LPPFFEGNGTET---
29 LPPFFEGNGTET---
30 LPPFCVGNGTESM--
31 ---------------
32 ---------------
33 ---------------
34 ---------------
35 EPPWQKNETYQFL--
36 ---------------
37 ---------------
38 ---------------
39 ---------------
40 ---------------
41 ---------------
42 ---------------
43 ---------------
44 ---------------
45 ---------------
46 ---------------
47 ---------------
48 AADLMAKN-------
49 ---------------
50 ---------------
51 ---------------
52 ---------------
53 ---------------
54 ---------------
55 ---------------
56 ---------------
57 ---------------
58 ---------------
59 ---------------
60 EPDYSAEEVADLL--
61 EEAYSIDDLQDA---
62 ---------------
63 ---------------
64 ---------------
65 QM-------------
66 ---------------
67 ---------------
68 LPPF-----------
69 ---------------
70 ---------------
71 ---------------
72 ---------------
73 ---------------
74 ---------------
75 ---------------
76 ---------------
77 ---------------
78 ---------------
79 QYNL-----------
80 ---------------
81 ---------------
82 ---------------
83 ---------------
84 ---------------
85 ---------------
86 ---------------
87 ---------------
88 ---------------
89 ---------------
90 ---------------
91 ---------------
92 ---------------
93 ---------------
94 ---------------
95 ---------------
96 ---------------
97 ---------------
98 ---------------
99 ---------------
100 ---------------
101 ---------------
102 ---------------
103 ---------------
104 ---------------
105 ---------------
106 ---------------
107 ---------------
108 ---------------
109 ---------------
110 ---------------
111 SFS------------
112 ---------------
113 ---------------
114 ---------------
115 ---------------
116 ---------------
117 ---------------
118 ---------------
119 ---------------
120 ---------------
121 ---------------
122 ---------------
123 ---------------
124 ---------------
125 ---------------
126 ---------------
127 ---------------
128 ---------------
129 ---------------
130 ---------------
131 ---------------
132 ---------------
133 ---------------
134 ---------------
135 ---------------
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147 ---------------