EvoFold predictions of conserved RNA structures in Drosophila Melanogaster
Prediction sets
These pages present EvoFold predictions of structural RNAs made using genome-wide 12-way multiz alignments.
The complete prediction set was divided into ranked subsets by two different approaches. First, based on size, shape, and genomic location, the complete set of predictions was divided into fold classes. The folds of each class were ranked according to the EvoFold score. Second, based on the classes of intergenic and intronic folds, a set of ncRNA candidates ranked by substitution evidence was also generated.
References
Stark A, Lin MF, Kheradpour P, Pedersen JS, Parts L, Carlson JW, Crosby MA, Rasmussen MD, Roy S, Deoras AN et al. Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature. 2007 Nov 8;450(7167):219-232.
Pedersen, J.S., Bejerano, G., Siepel, A., Rosenbloom, K., Lindblad-Toh, K., Lander, E., Rogers, J., Kent, J., Miller, W., and Haussler, D. Identification and Classification of Conserved RNA Secondary Structures in the Human Genome. PLoS Computat Biol 2(4), e33 (2006).