MaGnET

Malaria Genome Exploration Tool

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Datasets and sources


Gene and protein sequences and sequencing centre annotations

P. falciparum 3D7
Nuclear chromosomes:
Wellcome Trust Sanger Institute ftp site
Version 11/08/2009
Mitochondrial and plastid chromosomes:
PlasmoDB downloads

Version 5.3 June 2007
Original genome sequence publication: Gardner et al. Genome sequence of the human malaria parasite Plasmodium falciparum. (2002) Nature, 419: 498-511.

RNA-coding genes

P. falciparum 3D7
University of California, Santa Cruz Malaria genome browser 
Downloaded September 2007

Gene Ontology annotations

P. falciparum 3D7
Wellcome Trust Sanger Institute ftp site
Version 03/04/2008

InterPro predicted sequence features (domains etc)

P. falciparum 3D7
Wellcome Trust Sanger Institute ftp site
Version 14/08/2009

Ortholog/paralog groups

P. falciparum 3D7, P. vivax, P. knowlesi, P. berghei, P. c. chabaudi, P. y. yoelii
Wellcome Trust Sanger Institute ftp site
Data generated by OrthoMCL
Version 18/05/2009

Protein-protein interactions

P. falciparum 3D7
LaCount et al. A protein interaction network of the malaria parasite Plasmodium falciparum. (2005) Nature, 438(7064):103-7.

Protein experimentally-solved 3D structures

P. falciparum 3D7

RCSB Protein Data Bank
Last download: November 2007

Protein comparatively-modelled 3D structures

P. falciparum 3D7
ModBase 
Last download: November 2007

MRNA expression data

P. falciparum 3D7, Dd2 and HB3
Llinas et al. Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains. (2006) Nucleic Acids Research, 34(4): 1166-73. [website]
HB3 data originally from Bozdech et al. The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum. (2003) PLoS Biology, 1(1): e5.

P. falciparum 3D7 and NF54
Young et al. The Plasmodium falciparum sexual development transcriptome: A microarray analysis using ontology-based pattern identification. (2005) Molecular and Biochemical Parasitology, 143(1): 67-79. [website]

P. falciparum 3D7

Le Roch et al. Discovery of Gene Function by Expression Profiling of the Malaria Parasite Life Cycle. (2003) Science, 301(5639): 1503-8. [website]

MRNA decay data

P. falciparum 3D7
Shock et al. Whole-genome analysis of mRNA decay in Plasmodium falciparum reveals a global lengthening of mRNA half-life during intra-erythrocytic development cycle. (2007) Genome Biology, 8(7): R134.

Protein expression data

P. falciparum 3D7
Dataset was downloaded as a supplementary table from Le Roch et al. Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle. (2004) Genome Research, 14: 2308-18.
Original data from Florens et al. A proteomic view of the Plasmodium falciparum life cycle. (2002) Nature, 419: 520-26.

P. falciparum NF54
Lasonder et al. Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry. (2002) Nature, 419: 537-42.